Berberine as a potential anticancer agent: A comprehensive review

A Rauf, T Abu-Izneid, AA Khalil, M Imran, ZA Shah… - Molecules, 2021 - mdpi.com
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial
amount of research has been conducted to date to establish the anticancer potential of BBR …

Natural products for cancer therapy: a review of their mechanism of actions and toxicity in the past decade

YO Ali Abdalla, B Subramaniam… - Journal of Tropical …, 2022 - Wiley Online Library
The ethnopharmacological information gathered over many centuries and the presence of
diverse metabolites have made the medicinal plants as the prime source of drugs. Despite …

Analysis of the Coptis chinensis genome reveals the diversification of protoberberine-type alkaloids

Y Liu, B Wang, S Shu, Z Li, C Song, D Liu, Y Niu… - Nature …, 2021 - nature.com
Abstract Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales,
represents an important early-diverging eudicot lineage with diverse medicinal applications …

A natural isoquinoline alkaloid with antitumor activity: studies of the biological activities of berberine

D Liu, X Meng, D Wu, Z Qiu, H Luo - Frontiers in pharmacology, 2019 - frontiersin.org
Coptis, a traditional medicinal plant, has been used widely in the field of traditional Chinese
medicine for many years. More recently, the chemical composition and bioactivity of Coptis …

[HTML][HTML] Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling …

Y Liu, S Gong, K Li, G Wu, X Zheng, J Zheng… - Biomedicine & …, 2022 - Elsevier
Coptisine, one of the main active components of Rhizoma Coptidis, possesses anti-
inflammatory, antioxidant, anti-apoptosis and renoprotective effects. In this study, we …

Palmatine: a review of its pharmacology, toxicity and pharmacokinetics

J Long, J Song, L Zhong, Y Liao, L Liu, X Li - Biochimie, 2019 - Elsevier
Palmatine is a natural isoquinoline alkaloid and has been widely used in pharmaceutical
field. The purpose of this review is to provide the latest and comprehensive information on …

Targeting NF-κB pathway for treating ulcerative colitis: comprehensive regulatory characteristics of Chinese medicines

PD Lu, YH Zhao - Chinese medicine, 2020 - Springer
Nuclear factor-kappa B (NF-κB) is a kind of multi-functional nuclear transcription factor
involved in regulating gene transcription to influence pathological evolution of inflammatory …

Coptisine from Coptis chinensis exerts diverse beneficial properties: A concise review

J Wu, Y Luo, D Deng, S Su, S Li, L Xiang… - Journal of cellular …, 2019 - Wiley Online Library
Coptisine is a natural small‐molecular compound extracted from Coptis chinensis (CC) with
a history of using for thousands of years. This work aimed at summarizing coptisine's activity …

A recent update on the use of Chinese medicine in the treatment of inflammatory bowel disease

L Yang, H Luo, D Tan, S Zhang, Z Zhong, S Wang… - Phytomedicine, 2021 - Elsevier
Background Inflammatory bowel disease (IBD) is a chronic idiopathic disease that is
characterized by inflammation of the gastrointestinal tract. Proper management of IBD …

Current Advances in Coptidis Rhizoma for Gastrointestinal and Other Cancers

L He, Z Zhong, M Chen, Q Liang, Y Wang… - Frontiers in …, 2022 - frontiersin.org
Cancer is a serious disease with an increasing number of reported cases and high mortality
worldwide. Gastrointestinal cancer defines a group of cancers in the digestive system, eg …