The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …

S100B is a Ca2+‐binding protein mainly concentrated in astrocytes. Its levels in biological
fluids (cerebrospinal fluid, peripheral and cord blood, urine, saliva, amniotic fluid) are …

Although increasing evidence confirms neuropsychiatric manifestations associated mainly
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …

Alcohol use disorder (AUD) is a widespread disease with limited treatment options.
Targeting the neuroimmune system is a new avenue for developing or repurposing effective …

Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Postmortem investigations have implicated astrocytes in many neurological and psychiatric
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …

Abstract The use of Translocator Protein 18 kDa (TSPO) as a clinical neuroimaging
biomarker of brain injury and neuroinflammation has increased exponentially in the last …

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor encoded by NFE2L2.
Under oxidative stress, Nrf2 does not undergo its normal cytoplasmic degradation but …

Background and Objectives Although patients hospitalized with COVID-19 frequently
present with encephalopathy, those with mild initial COVID-19 disease who never required …

Schizophrenia is a severe and clinically heterogenous mental disorder affecting
approximately 1% of the population worldwide. Despite tremendous achievements in the …