The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

Abstract The Research Domain Criteria (RDoC), developed by the National Institute of
Mental Health as a neuroscience-informed alternative to traditional psychiatric nosology, is …

Ventral midbrain dopaminergic neurons project to the striatum as well as the cortex and are
involved in movement control and reward-related cognition. In Parkinson's disease …

Attention-deficit/hyperactivity disorder (ADHD) is a common and impairing disorder affecting
children, adolescents, and adults. Several treatment strategies are available that can …

In many circumstances alternative courses of action and thoughts have to be inhibited to
allow the emergence of goal-directed behavior. However, this has not been the accepted …

Abstract Attention Deficit Hyperactivity Disorder (ADHD) is a persistent, and impairing
pediatric-onset neurodevelopmental condition. Its high prevalence, and recurrent …

Controversy abounds regarding the symptom dimensions of attention problems, impulsivity,
and hyperactivity, developmentally extreme and impairing levels of which compose the …

Background Two objectives of the NIMH Research Domain Criteria (RDoC) initiative are to
identify (a) mechanisms that are common to multiple psychiatric disorders, and (b) …

Accumulating evidence shows that oxidative stress is involved in a wide variety of human
diseases: rheumatoid arthritis, Alzheimer's disease, Parkinson's disease, cancers, etc. Here …