Developmental and epileptic encephalopathies: recognition and approaches to care

S Raga, N Specchio, S Rheims… - Epileptic …, 2021 - Wiley Online Library
The term “developmental and epileptic encephalopathy”(DEE) refers to when cognitive
functions are influenced by both seizure and interictal epileptiform activity and the …

Modeling epileptic spasms during infancy: Are we heading for the treatment yet?

L Velíšek, J Velíšková - Pharmacology & therapeutics, 2020 - Elsevier
Infantile spasms (IS or epileptic spasms during infancy) were first described by Dr. William
James West (aka West syndrome) in his own son in 1841. While rare by definition (occurring …

The impact of hypsarrhythmia on infantile spasms treatment response: observational cohort study from the National Infantile Spasms Consortium

ST Demarest, RA Shellhaas, WD Gaillard, C Keator… - …, 2017 - Wiley Online Library
Summary Objective The multicenter National Infantile Spasms Consortium prospective
cohort was used to compare outcomes and phenotypic features of patients with infantile …

Long-term epilepsy control, motor function, cognition, sleep and quality of life in children with West syndrome

S Bhanudeep, P Madaan, N Sankhyan, L Saini… - Epilepsy Research, 2021 - Elsevier
Purpose To assess epilepsy, motor function, cognitive, sleep, and quality of life outcomes
and their predictors in a follow-up cohort with West syndrome (WS) at≥ 5 years of age …

[HTML][HTML] Epilepsy and neurodevelopmental outcomes in a cohort of West syndrome beyond two years of age

R Aramanadka, JK Sahu, P Madaan… - Indian journal of …, 2022 - Springer
Objective To determine epilepsy and neurodevelopmental outcomes beyond 2 y of age and
their putative prognostic factors in children with West syndrome (WS). Methods This cross …

Epilepsy outcome at four years in a randomized clinical trial comparing oral prednisolone and intramuscular ACTH in west syndrome

J Wanigasinghe, C Arambepola, SS Ranganathan… - Pediatric Neurology, 2021 - Elsevier
Background This article explores the role of initial treatment on control of spasms and other
epilepsies at four years in children previously treated for West syndrome. Methods The Sri …

[HTML][HTML] Neurological development, epilepsy, and the pharmacotherapy approach in children with congenital Zika syndrome: results from a two-year follow-up study

ME Quilião, FA Venancio, LK Mareto, SA Metzker… - Viruses, 2020 - mdpi.com
Clinical outcomes related to congenital Zika syndrome (CZS) include microcephaly
accompanied by specific brain injuries. Among several CZS outcomes that have been …

[HTML][HTML] Prediction model for long-term seizure and developmental outcomes among children with infantile epileptic spasms syndrome

Y Arai, T Okanishi, S Kanai, Y Nakamura… - Frontiers in …, 2023 - frontiersin.org
Introduction Children with infantile epileptic spasms syndrome (IESS) are likely to
experience poor outcomes. Researchers have investigated the factors related to its long …

[HTML][HTML] Retrospective clinical analysis of epilepsy treatment for children with drug-resistant epilepsy (A single-center experience)

C Liu, Y Hu, J Zhou, Y Guan, M Wang, X Qi, X Wang… - Brain Sciences, 2022 - mdpi.com
Objectives: This retrospective cohort study investigated the clinical characteristics and
seizure outcomes of patients aged 1–14 years with drug-resistant epilepsy (DRE) who were …

Evaluation of ten prognostic factors affecting the outcome of West syndrome

S Yilmaz, H Tekgul, G Serdaroglu, A Akcay… - Acta Neurologica …, 2016 - Springer
The aim of this study is to assess the seizure and developmental outcome and to determine
the prognostic factors affecting the outcome of West syndrome in an etiologically well …