Effects of intensive blood pressure reduction on myocardial infarction and stroke in diabetes: a meta-analysis in 73 913 patients
Objective Guidelines generally recommend intensive lowering of blood pressure (BP) in
patients with type 2 diabetes. There is uncertainty about the impact of this strategy on case …
patients with type 2 diabetes. There is uncertainty about the impact of this strategy on case …
[HTML][HTML] Expanding the horizon of EV-RNAs: LncRNAs in EVs as biomarkers for disease pathways
Extracellular vesicles (EVs) are membrane-bound nanoparticles with different types of cargo
released by cells and postulated to mediate functions such as intercellular communications …
released by cells and postulated to mediate functions such as intercellular communications …
Protective effect of bone marrow mesenchymal stem cell-derived exosomes on cardiomyoblast hypoxia-reperfusion injury through the miR-149/let-7c/Faslg axis
L Zou, X Ma, B Wu, Y Chen, D Xie, C Peng - Free radical research, 2020 - Taylor & Francis
Ischaemia-reperfusion injury (IRI) is closely related to cardiovascular disease (CVD), which
is the leading cause of death and disability. Exosomes appear to be involved in several …
is the leading cause of death and disability. Exosomes appear to be involved in several …
Chronic Co-Administration of Sepiapterin and l-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 …
SL Baumgardt, M Paterson, TM Leucker… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Diabetic heart disease is associated with tetrahydrobiopterin oxidation and
high arginase activity, leading to endothelial nitric oxide synthase dysfunction. Sepiapterin …
high arginase activity, leading to endothelial nitric oxide synthase dysfunction. Sepiapterin …
Genetic association of Glutathione peroxidase-1 (GPx-1) and NAD(P)H:Quinone Oxidoreductase 1(NQO1) variants and their association of CAD in …
T Ramprasath, PS Murugan, E Kalaiarasan… - Molecular and cellular …, 2012 - Springer
Coronary artery disease (CAD) is a major health concern and the leading cause of death in
individuals with type-2 diabetes mellitus (T2DM). Glutathione peroxidase-1 (GPx-1) and …
individuals with type-2 diabetes mellitus (T2DM). Glutathione peroxidase-1 (GPx-1) and …
Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart
T Okazaki, H Otani, T Shimazu, K Yoshioka… - Journal of Molecular and …, 2011 - Elsevier
The diabetic heart is known to be susceptible to ischemia/reperfusion (I/R) injury by
increased oxidative stress. Although oxidative stress upregulates inducible nitric oxide …
increased oxidative stress. Although oxidative stress upregulates inducible nitric oxide …
Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart
T Okazaki, H Otani, T Shimazu, K Yoshioka… - Free radical …, 2011 - Taylor & Francis
Oxidative stress may cause a loss of tetrahydrobiopterin (BH4), a co-factor of nitric oxide
synthase (NOS), decrease the bioavailability of NO and aggravate ischemia/reperfusion (I/R) …
synthase (NOS), decrease the bioavailability of NO and aggravate ischemia/reperfusion (I/R) …
GLP‐1 is a coronary artery vasodilator in humans
Background The mechanism underlying the beneficial cardiovascular effects of the incretin
GLP‐1 (glucagon‐like peptide 1) and its analogues in humans is elusive. We hypothesized …
GLP‐1 (glucagon‐like peptide 1) and its analogues in humans is elusive. We hypothesized …
Calcium-dependent ultrasound stimulation of secretory events from pancreatic beta cells
I Suarez Castellanos, T Singh, B Balteanu… - Journal of therapeutic …, 2017 - Springer
Background Our previous studies have indicated that ultrasound can stimulate the release of
insulin from pancreatic beta cells, providing a potential novel treatment for type 2 diabetes …
insulin from pancreatic beta cells, providing a potential novel treatment for type 2 diabetes …
Étude des modifications structurales et fonctionnelles de l'albumine dans le diabète de type 2: identification de biomarqueurs de glycoxydation et de facteurs de risque …
A Guérin-Dubourg - 2014 - theses.hal.science
La mortalité du diabète de type 2 est liée à ses complications cardiovasculaires (CVD).
L'identification de nouveaux biomarqueurs associés à la dysfonction endothéliale …
L'identification de nouveaux biomarqueurs associés à la dysfonction endothéliale …