Kinins are among the most potent autacoids involved in inflammatory, vascular and pain
processes. These short-lived peptides, including bradykinin, kallidin and T-kinin, are …

In 1949, Rocha e Silva and collaborators reported the existence of a new relaxing
substance, liberated in plasma by the action of the snake venom of Bothrops jararaca or by …

In the present paper we discuss, based in our experience, some experimental procedures
which may be employed for isolation of active compounds from medicinal plants. We have …

Kinins are a family of peptides implicated in several pathophysiological events. Most of their
effects are likely mediated by the activation of two G‐protein‐coupled receptors: B1 and B2 …

<!? tlsb=. 005w> Caffeic acid and some of its derivatives such as caffeic acid phenetyl ester
(CAPE) and octyl caffeate are potent antioxidants which present important anti-inflammatory …

The necessity of safe and effective treatments for chronic pain has intensified the search for
new analgesic drugs. In the last few years, members of a closely-related family of ion …

The popular medicine Passiflora edulis has been used as a sedative, tranquilizer, against
cutaneous inflammatory diseases and intermittent fever. Most of the pharmacological …

The composition of eight samples of commercial copaiba oils, used in the Amazonian region
as antiinflammatory agents and available in popular markets, were analysed by gas …

Disease and injury frequently result in pain and hyperalgesia. These abnormal sensory
events arise in part from the action of inflammatory mediators on the peripheral terminals of …

Ischemic stroke is a leading cause of death and disability worldwide. Increasing evidence
indicates that ischemic stroke is a thromboinflammatory disease in which the contact–kinin …