Anti-inflammatory and M2 macrophage polarization-promoting effect of mesenchymal stem cell-derived exosomes
M Arabpour, A Saghazadeh, N Rezaei - International …, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells beneficial in regenerative medicine
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
and tissue repair. The therapeutic potential of MSCs for inflammatory diseases and …
Extracellular vesicles: A bright star of nanomedicine
P Wu, B Zhang, DKW Ocansey, W Xu, H Qian - Biomaterials, 2021 - Elsevier
Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …
characteristics as well as predominant physiochemical stability and biocompatibility …
Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
Molecular mechanisms responsible for therapeutic potential of mesenchymal stem cell-derived secretome
CR Harrell, C Fellabaum, N Jovicic, V Djonov… - Cells, 2019 - mdpi.com
Mesenchymal stem cell (MSC)-sourced secretome, defined as the set of MSC-derived
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …
bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed …
Mesenchymal stem cell-derived secretome: a potential therapeutic option for autoimmune and immune-mediated inflammatory diseases
G Műzes, F Sipos - Cells, 2022 - mdpi.com
Immune-mediated inflammatory diseases (IMIDs) encompass several entities such as
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …
“classic” autoimmune disorders or immune-mediated diseases with autoinflammatory …
Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer
Exosomes hold great potential for cancer treatment to deliver therapeutics due to its inherent
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …
Extracellular vesicles as a drug delivery system: A systematic review of preclinical studies
During the past decades, extracellular vesicles (EVs) have emerged as an attractive drug
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
delivery system. Here, we assess their pre-clinical applications, in the form of a systematic …
Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls
M Heidarzadeh, Y Gürsoy-Özdemir, M Kaya… - Cell & Bioscience, 2021 - Springer
Nowadays, a large population around the world, especially the elderly, suffers from
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …
neurological inflammatory and degenerative disorders/diseases. Current drug delivery …
Preconditioning and Engineering Strategies for Improving the Efficacy of Mesenchymal Stem Cell‐Derived Exosomes in Cell‐Free Therapy
S Chen, F Sun, H Qian, W Xu, J Jiang - Stem cells international, 2022 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely applied to regenerative medicine owing
to their multiple differentiation, self‐renewal, and immunomodulatory abilities. Exosomes are …
to their multiple differentiation, self‐renewal, and immunomodulatory abilities. Exosomes are …
Application of extracellular vesicles derived from mesenchymal stem cells as potential therapeutic tools in autoimmune and rheumatic diseases
Mesenchymal stem cells (MSCs) have been proven to have superior potential to be used as
therapeutic candidates in various disorders. Nevertheless, the clinical application of these …
therapeutic candidates in various disorders. Nevertheless, the clinical application of these …