Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1

W Czestkowski, Ł Krzemiński… - Journal of medicinal …, 2024 - ACS Publications
Chitinase-3-like-1 (CHI3L1), also known as YKL-40, is a glycoprotein linked to inflammation,
fibrosis, and cancer. This study explored CHI3L1's interactions with various …