Stress is a state of the mind, involving both brain and body as well as their interactions; it
differs among individuals and reflects not only major life events but also the conflicts and …

As the central organ of stress and adaptation to stressors, the brain plays a pivotal role in
behavioral and physiological responses that may lead to successful adaptation or to …

The brain is the key organ of stress reactivity, coping, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

This article is part of a Special Issue “Parental Care”. Early mother–infant relationships play
important roles in infants' optimal development. New mothers undergo neurobiological …

The brain is the key organ of stress processes. It determines what individuals will experience
as stressful, it orchestrates how individuals will cope with stressful experiences, and it …

Although approximately 90% of the US population will experience a traumatic event within
their lifetime, only a fraction of those traumatized individuals will develop posttraumatic …

Major depressive disorder (MDD) has until recently been conceptualized as an episodic
disorder associated with 'chemical imbalances' but no permanent brain changes. Evidence …

Animal studies suggest that structural changes occur in the maternal brain during the early
postpartum period in regions such as the hypothalamus, amygdala, parietal lobe, and …

BACKGROUND: Cumulative adversity and stress are associated with risk of psychiatric
disorders. While basic science studies show repeated and chronic stress effects on …

We draw on the theory of allostasis to develop an integrative model of the current stress
process that highlights the brain as a dynamically adapting interface between the changing …