The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

The objective of this manuscript is to provide quantitative insights into the tissue distribution
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …

Large-scale, unbiased proteomics studies are constrained by the complexity of the plasma
proteome. Here we report a highly parallel protein quantitation platform integrating …

Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Upon contact with a biological milieu, nanomaterials tend to interact with biomolecules
present in the media, especially proteins, leading to the formation of the so-called “protein …

The technology of drug delivery systems (DDSs) has demonstrated an outstanding
performance and effectiveness in production of pharmaceuticals, as it is proved by many …

Isothermal titration calorimetry (ITC) is a complementary technique that can be used for
investigations of protein adsorption on nanomaterials, as it quantifies the thermodynamic …

This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …

Protein corona formation is critical for the design of ideal and safe nanoparticles (NPs) for
nanomedicine, biosensing, organ targeting, and other applications, but methods to …

Encapsulation of biomacromolecules in metal–organic frameworks (MOFs) can preserve
biological functionality in harsh environments. Despite the success of this approach, termed …