Myopia is one of the leading ocular disorders causing visual impairment worldwide, with the
prevalence increasing rapidly. It's a significant global public health concern in 21st century …

Myopia is the most common eye condition leading to visual impairment and is greatly
influenced by genetics. Over the last two decades, more than 400 associated gene loci have …

Purpose.: To evaluate variants in the LRPAP1, CTSH, LEPREL1, ZNF644, SLC39A5, and
SCO2 genes in 298 unrelated patients with early-onset high myopia (eoHM). Methods …

Myopia is the most common cause of visual impairment worldwide. Genetic and
environmental factors contribute to the development of myopia. Studies on the molecular …

Purpose.: Two recent large-scale genome-wide association studies identified significant
associations between myopia and single nucleotide polymorphisms (SNPs) near the …

The focus of this update is to emphasize the recent advances in the pathogenesis and
various molecular key approaches associated with myopia in order to reveal new potential …

Myopia, commonly referred to as nearsightedness, is one of the most common causes of
visual disability throughout the world. It affects more people worldwide than any other …

Myopia is a substantial global public health concern primarily linked to the elongation of the
axial length of the eyeball. While numerous animal models have been employed to …

Myopia is a major cause of visual impairment worldwide. In particular, high myopia is
associated with serious blinding complications, including retinal detachment, chorioretinal …

Purpose: To assess residual cone structure in subjects with mutations in exon 2, 3, and 4 of
the OPN1LW or OPN1MW opsin. Methods: Thirteen males had their OPN1LW/OPN1MW …