Update on anticytokine treatment for asthma

L Gallelli, MT Busceti, A Vatrella… - BioMed research …, 2013 - Wiley Online Library
Current advances in the knowledge of asthma pathobiology suggest that anticytokine
therapies can be potentially useful for the treatment of this complex and heterogeneous …

Overview of antiviral drug therapy for COVID-19: where do we stand?

R Esposito, D Mirra, L Sportiello, G Spaziano… - Biomedicines, 2022 - mdpi.com
The vaccine weapon has resulted in being essential in fighting the COVID-19 outbreak, but it
is not fully preventing infection due to an alarming spreading of several identified variants of …

Lung microRNAs expression in lung cancer and COPD: a preliminary study

D Mirra, R Esposito, G Spaziano, C La Torre, C Vocca… - Biomedicines, 2023 - mdpi.com
Non-small cell lung cancer (NSCLC) is one of the deadliest diseases worldwide and
represents an impending burden on the healthcare system. Despite increasing attention, the …

MicroRNA Monitoring in Human Alveolar Macrophages from Patients with Smoking-Related Lung Diseases: A Preliminary Study

D Mirra, R Esposito, G Spaziano, L Sportiello, F Panico… - Biomedicines, 2024 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a progressive lung disease that is
commonly considered to be a potent driver of non-small cell lung cancer (NSCLC) …

Circulating microRNAs expression profile in lung inflammation: A preliminary study

D Mirra, E Cione, G Spaziano, R Esposito… - Journal of Clinical …, 2022 - mdpi.com
Background: Bronchial asthma is an inflammatory airway disease with an ever-increasing
incidence. Therefore, innovative management strategies are urgently needed. MicroRNAs …

The rabbit as a model to study asthma and other lung diseases

S Keir, C Page - Pulmonary pharmacology & therapeutics, 2008 - Elsevier
No single animal model is able to reproduce all the features of human asthma. However, the
similarities between neonatally immunised rabbits and human asthma highlight the value of …

Potential therapeutic targets for neurokinin-1 receptor antagonists

RA Duffy - Expert opinion on emerging drugs, 2004 - Taylor & Francis
The peptide substance P and its tachykinin receptor, neurokinin-1 (NK1), have been the
focus of considerable research for their role in a variety of both central and peripheral …

Intratracheal administration of mesenchymal stem cells modulates tachykinin system, suppresses airway remodeling and reduces airway hyperresponsiveness in an …

K Urbanek, A De Angelis, G Spaziano, E Piegari… - PLoS …, 2016 - journals.plos.org
Background The need for new options for chronic lung diseases promotes the research on
stem cells for lung repair. Bone marrow-derived mesenchymal stem cells (MSCs) can …

Dorsal vagal complex modulates neurogenic airway inflammation in a guinea pig model with esophageal perfusion of HCl

Z Chen, L Sun, H Chen, D Gu, W Zhang… - Frontiers in …, 2018 - frontiersin.org
Neurogenic airway inflammation in chronic cough and bronchial asthma related to
gastroesophageal reflux (GER) is involved in the esophageal–bronchial reflex, but it is …

Бронхолегочные проявления гастроэзофагеальной рефлюксной болезни: особенности патогенеза, клиники и диагностики

ДН Абдулманапова, НУ Чамсутдинов - Современные проблемы науки …, 2013 - elibrary.ru
Проведен обзор литературы по бронхолегочным проявлениям гастроэзофагеальной
рефлюксной болезни (ГЭРБ). Отмечается, что в России, как и во всем мире …