Multiple mechanisms of anti-cancer effects exerted by astaxanthin

L Zhang, H Wang - Marine drugs, 2015 - mdpi.com
Astaxanthin (ATX) is a xanthophyll carotenoid which has been approved by the United
States Food and Drug Administration (USFDA) as food colorant in animal and fish feed. It is …

Emerging molecular therapeutic targets for cholangiocarcinoma

SI Ilyas, GJ Gores - Journal of hepatology, 2017 - Elsevier
Cholangiocarcinomas (CCAs) are diverse epithelial tumors arising from the liver or large
bile ducts with features of cholangiocyte differentiation. CCAs are classified anatomically …

Suppression of hepatocellular carcinoma by baculovirus-mediated expression of long non-coding RNA PTENP1 and MicroRNA regulation

CL Chen, YW Tseng, JC Wu, GY Chen, KC Lin… - Biomaterials, 2015 - Elsevier
Long non-coding RNAs (lncRNAs) play regulatory roles in cancers. LncRNA PTENP1 is a
pseudogene of the tumor suppressor gene PTEN but its roles in hepatocellular carcinoma …

Spinal cord regeneration

W Young - Cell transplantation, 2014 - journals.sagepub.com
Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Cell Trafficking at the Intersection of the Tumor–Immune Compartments

W Du, P Nair, A Johnston, PH Wu… - Annual review of …, 2022 - annualreviews.org
Migration is an essential cellular process that regulates human organ development and
homeostasis as well as disease initiation and progression. In cancer, immune and tumor cell …

Signalling networks in cholangiocarcinoma: Molecular pathogenesis, targeted therapies and drug resistance

L Fouassier, M Marzioni, MB Afonso… - Liver …, 2019 - Wiley Online Library
Cholangiocarcinoma (CCA) is a deadly disease. While surgery may attain cure in a minor
fraction of cases, therapeutic options in either the adjuvant or advanced setting are limited …

[HTML][HTML] Targeting cholangiocarcinoma

JC Mertens, SI Ilyas, GJ Gores - … et Biophysica Acta (BBA)-Molecular Basis …, 2018 - Elsevier
Cholangiocarcinoma (CCA) represents a diverse group of epithelial cancers associated with
the biliary tract, and can best be stratified anatomically into intrahepatic (iCCA), perihilar …

Resveratrol interrupts the pro-invasive communication between cancer associated fibroblasts and cholangiocarcinoma cells

S Thongchot, A Ferraresi, C Vidoni, W Loilome… - Cancer letters, 2018 - Elsevier
Cholangiocarcinoma (CCA), the cancer arising from the epithelial cells of bile ducts, is a
prototype of inflammatory-driven cancer. Cytokines released by cancer associated …

Mitogen-activated protein kinases (MAPKs) and cholangiocarcinoma: the missing link

C Chen, LJ Nelson, MA Ávila, FJ Cubero - Cells, 2019 - mdpi.com
In recent years, the incidence of both liver and biliary tract cancer has increased.
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) are the two most common …

A blockade of PD-L1 produced antitumor and antimetastatic effects in an orthotopic mouse pancreatic cancer model via the PI3K/Akt/mTOR signaling pathway

L Zhao, C Li, F Liu, Y Zhao, J Liu, Y Hua… - OncoTargets and …, 2017 - Taylor & Francis
Background Pancreatic cancer is one of the most aggressive and intractable malignant
tumors, and most deaths from pancreatic cancer are related to metastases. It has been …