Structural variant calling: the long and the short of it
Recent research into structural variants (SVs) has established their importance to medicine
and molecular biology, elucidating their role in various diseases, regulation of gene …
and molecular biology, elucidating their role in various diseases, regulation of gene …
You are what you eat: diet, health and the gut microbiota
Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces shaping the architecture and functionality of resident …
accumulated in comprehending forces shaping the architecture and functionality of resident …
[HTML][HTML] Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of …
ER Riggs, EF Andersen, AM Cherry, S Kantarci… - 2020 - Elsevier
Purpose Copy-number analysis to detect disease-causing losses and gains across the
genome is recommended for the evaluation of individuals with neurodevelopmental …
genome is recommended for the evaluation of individuals with neurodevelopmental …
NextDenovo: an efficient error correction and accurate assembly tool for noisy long reads
Long-read sequencing data, particularly those derived from the Oxford Nanopore
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …
Origins and genetic legacy of prehistoric dogs
Dogs were the first domestic animal, but little is known about their population history and to
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …
Vaginal microbiome: normalcy vs dysbiosis
VS Saraf, SA Sheikh, A Ahmad, PM Gillevet… - Archives of …, 2021 - Springer
It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …
physiological environment for the host and its involvement is deemed indispensable for …
Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …
[图书][B] Darwin's unfinished symphony: How culture made the human mind
KN Laland - 2017 - degruyter.com
Humans possess an extraordinary capacity for cultural production, from the arts and
language to science and technology. How did the human mind—and the uniquely human …
language to science and technology. How did the human mind—and the uniquely human …
Finding the genomic basis of local adaptation: pitfalls, practical solutions, and future directions
Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …
evolutionary biology. The recent development of cost-effective methods for obtaining high …
[图书][B] The secret of our success: How culture is driving human evolution, domesticating our species, and making us smarter
J Henrich - 2016 - degruyter.com
Humans are a puzzling species. On the one hand, we struggle to survive on our own in the
wild, often failing to overcome even basic challenges, like obtaining food, building shelters …
wild, often failing to overcome even basic challenges, like obtaining food, building shelters …