Recent research into structural variants (SVs) has established their importance to medicine
and molecular biology, elucidating their role in various diseases, regulation of gene …

Since the renaissance of microbiome research in the past decade, much insight has
accumulated in comprehending forces shaping the architecture and functionality of resident …

Purpose Copy-number analysis to detect disease-causing losses and gains across the
genome is recommended for the evaluation of individuals with neurodevelopmental …

Long-read sequencing data, particularly those derived from the Oxford Nanopore
sequencing platform, tend to exhibit high error rates. Here, we present NextDenovo, an …

Dogs were the first domestic animal, but little is known about their population history and to
what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that …

It has been long understood that the vaginal microflora is crucial in maintaining a normal
physiological environment for the host and its involvement is deemed indispensable for …

Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

Humans possess an extraordinary capacity for cultural production, from the arts and
language to science and technology. How did the human mind—and the uniquely human …

Uncovering the genetic and evolutionary basis of local adaptation is a major focus of
evolutionary biology. The recent development of cost-effective methods for obtaining high …

Humans are a puzzling species. On the one hand, we struggle to survive on our own in the
wild, often failing to overcome even basic challenges, like obtaining food, building shelters …