[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

Extracellular vesicles as regulators of the extracellular matrix

NJ Patel, A Ashraf, EJ Chung - Bioengineering, 2023 - mdpi.com
Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the
extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids …

Pioneer role of extracellular vesicles as modulators of cancer initiation in progression, drug therapy, and vaccine prospects

S Jahan, S Mukherjee, S Ali, U Bhardwaj… - Cells, 2022 - mdpi.com
Cancer is one of the leading diseases, causing deaths worldwide. Nearly 10 million deaths
were reported in 2020 due to cancer alone. Several factors are involved in cancer …

Liver metastasis from colorectal cancer: pathogenetic development, immune landscape of the tumour microenvironment and therapeutic approaches

Y Wang, X Zhong, X He, Z Hu, H Huang, J Chen… - Journal of Experimental …, 2023 - Springer
Colorectal cancer liver metastasis (CRLM) is one of the leading causes of death among
patients with colorectal cancer (CRC). Although immunotherapy has demonstrated …

Recent advancement and technical challenges in developing small extracellular vesicles for cancer drug delivery

T Geng, P Pan, E Leung, Q Chen, L Chamley… - Pharmaceutical …, 2021 - Springer
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
enclosed vesicles and act like 'messages in a bottle'in cell-cell communication by …

The roles of extracellular vesicles in malignant melanoma

YC Cheng, YA Chang, YJ Chen, HM Sung, I Bogeski… - Cells, 2021 - mdpi.com
Different types of cells, such as endothelial cells, tumor-associated fibroblasts, pericytes, and
immune cells, release extracellular vesicles (EVs) in the tumor microenvironment. The …

Multiomics of colorectal cancer organoids reveals putative mediators of cancer progression resulting from SMAD4 inactivation

JJ Dijkstra, HK Neikes, S Rezaeifard, X Ma… - Journal of Proteome …, 2022 - ACS Publications
The development of metastasis severely reduces the life expectancy of patients with
colorectal cancer (CRC). Although loss of SMAD4 is a key event in CRC progression, the …

Radiogenomics: hunting down liver metastasis in colorectal cancer patients

C de la Pinta, ME Castillo, M Collado… - Cancers, 2021 - mdpi.com
Simple Summary Colorectal cancer (CRC) is the third leading cause of cancer and the
second most deadly tumor type in the world. The liver is the most common site of metastasis …

Exosomes: emerging diagnostic and therapeutic targets in cutaneous diseases

AQ Khan, S Akhtar, KS Prabhu, L Zarif, R Khan… - International Journal of …, 2020 - mdpi.com
Skin is the largest human organ and is continuously exposed to various exogenous and
endogenous trigger factors affecting body homeostasis. A number of mechanisms, including …

Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer

A Raza, AQ Khan, VP Inchakalody, S Mestiri… - Journal of Experimental …, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide. The diagnosis,
prognosis and therapeutic monitoring of CRC depends largely on tissue biopsy. However …