Regulation of amino acid's biosynthetic pathway is of significant importance to maintain
homeostasis and cell functions. Amino acids regulate their biosynthetic pathway by end …

The cysteine biosynthetic pathway is of fundamental importance for the growth, survival, and
pathogenicity of the many pathogens. This pathway is present in many species but is absent …

Cysteine biosynthesis takes place via a two-step pathway in bacteria, fungi, plants and
protozoan parasites, but not in humans, and hence, the machinery of cysteine biosynthesis …

In most bacteria and plants, direct biosynthesis of cysteine from sulfide via O-acetylserine
(OAS) is essential to produce sulfur amino acids from inorganic sulfur. Here, we report the …

Brucella abortus is the major cause of premature foetal abortion in cattle, can be transmitted
from cattle to humans, and is considered a powerful biological weapon. De novo cysteine …

Serine acetyltransferase (SAT) catalyzes the acetylation of l-serine in the first step of the two-
step pathway to synthesize L-cysteine in bacteria, protozoans and plants. L-cysteine is …

Serine acetyl transferase (SAT) is one of the crucial enzymes in the cysteine biosynthetic
pathway and an essential enzyme for the survival of Entamoeba histolytica, the causative …

In contrast to mammalian cells, bacteria such as Escherichia coli have been shown to
display tolerance towards the neurotoxin β-methylamino-l-alanine (BMAA) suggesting that …

In the fight against bacterial infections and antibiotic resistance, the dapE-encoded N-
succinyl-l, l-diaminopimelic acid desuccinylase (DapE) is a potentially safe target enzyme …

World Health Organization (WHO) reports that one-third of the world's population is infected
with a persistent form of Mycobacterium tuberculosis (M. tb), the causative bacterium …