Since the discovery of sickle cell disease (SCD) in 1910, enormous strides have been made
in the elucidation of the pathogenesis of its protean complications, which has inspired recent …

Red blood cells (RBCs) are a specialised organ that enabled the evolution of multicellular
organisms by supplying a sufficient quantity of oxygen to cells that cannot obtain oxygen …

Using aqueous cyanobacterial extracts in the synthesis of silver nanoparticle is looked as
green, ecofriendly, low priced biotechnology that gives advancement over both chemical …

Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Hemolysis is a fundamental feature of sickle cell anemia that contributes to its
pathophysiology and phenotypic variability. Decompartmentalized hemoglobin, arginase 1 …

Abstract Ravulizumab (ALXN1210), a new complement C5 inhibitor, provides immediate,
complete, and sustained C5 inhibition. This phase 3, open-label study assessed the …

New evidence has stirred up a long‐standing but undeservedly forgotten interest in the role
of erythrocytes, or red blood cells (RBCs), in blood clotting and its disorders. This review …

Deformability is an essential feature of blood cells (RBCs) that enables them to travel
through even the smallest capillaries of the human body. Deformability is a function of (i) …

Breakthrough Hemolysis in PNH with Proximal or Terminal Complement Inhibition | New
England Journal of Medicine Skip to main content The New England Journal of Medicine …

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare bone marrow failure disorder that
manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias. The …