Aneurysmal subarachnoid hemorrhage: the last decade

SN Neifert, EK Chapman, ML Martini… - Translational stroke …, 2021 - Springer
Aneurysmal subarachnoid hemorrhage (SAH) affects six to nine people per 100,000 per
year, has a 35% mortality, and leaves many with lasting disabilities, often related to cognitive …

Early brain injury after subarachnoid hemorrhage: incidence and mechanisms

DC Lauzier, K Jayaraman, JY Yuan, D Diwan… - Stroke, 2023 - Am Heart Assoc
Aneurysmal subarachnoid hemorrhage is a devastating condition causing significant
morbidity and mortality. While outcomes from subarachnoid hemorrhage have improved in …

Diagnosis and treatment of unruptured intracranial aneurysms and aneurysmal subarachnoid hemorrhage

RG Tawk, TF Hasan, CE D'Souza, JB Peel… - Mayo Clinic …, 2021 - Elsevier
Unruptured intracranial aneurysms (UIAs) are commonly acquired vascular lesions that form
an outpouching of the arterial wall due to wall thinning. The prevalence of UIAs in the …

Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study

JP Dreier, MKL Winkler, S Major, V Horst, S Lublinsky… - Brain, 2022 - academic.oup.com
Focal brain damage after aneurysmal subarachnoid haemorrhage predominantly results
from intracerebral haemorrhage, and early and delayed cerebral ischaemia. The …

[HTML][HTML] Heat shock protein 22 modulates NRF1/TFAM-dependent mitochondrial biogenesis and DRP1-sparked mitochondrial apoptosis through AMPK-PGC1α …

H Fan, R Ding, W Liu, R Li, B Wei, S Su, F Jin, C Wei… - Redox biology, 2021 - Elsevier
Mitochondrial dysfunction has been widely accepted as a detrimental factor in subarachnoid
hemorrhage (SAH)-induced early brain injury (EBI), which is eminently related to poor …

Modifiable risk factors for intracranial aneurysm and aneurysmal subarachnoid hemorrhage: a mendelian randomization study

V Karhunen, MK Bakker, YM Ruigrok… - Journal of the …, 2021 - Am Heart Assoc
Background The aim of this study was to assess the associations of modifiable lifestyle
factors (smoking, coffee consumption, sleep, and physical activity) and cardiometabolic …

Inflammation and immune cell abnormalities in intracranial aneurysm subarachnoid hemorrhage (SAH): relevant signaling pathways and therapeutic strategies

J Jin, J Duan, L Du, W Xing, X Peng… - Frontiers in …, 2022 - frontiersin.org
Intracranial aneurysm subarachnoid hemorrhage (SAH) is a cerebrovascular disorder
associated with high overall mortality. Currently, the underlying mechanisms of pathological …

European Stroke Organisation (ESO) guidelines on management of unruptured intracranial aneurysms

N Etminan, DA de Sousa, C Tiseo… - European stroke …, 2022 - journals.sagepub.com
Unruptured intracranial aneurysms (UIA) occur in around 3% of the population. Important
management questions concern if and how to perform preventive UIA occlusion; if, how and …

Gut microbiota and acute central nervous system injury: a new target for therapeutic intervention

B Yuan, X Lu, Q Wu - Frontiers in immunology, 2021 - frontiersin.org
Acute central nervous system (CNS) injuries, including stroke, traumatic brain injury (TBI),
and spinal cord injury (SCI), are the common causes of death or lifelong disabilities …

Subarachnoid hemorrhage

S Muehlschlegel - Continuum: Lifelong Learning in Neurology, 2018 - journals.lww.com
PURPOSE OF REVIEW This article reviews the epidemiology, clinical presentation,
diagnosis, and management of patients with aneurysmal subarachnoid hemorrhage (SAH) …