Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands

S Cecioni, A Imberty, S Vidal - Chemical reviews, 2015 - ACS Publications
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …

Multivalency as a chemical organization and action principle

C Fasting, CA Schalley, M Weber… - Angewandte Chemie …, 2012 - Wiley Online Library
Multivalent interactions can be applied universally for a targeted strengthening of an
interaction between different interfaces or molecules. The binding partners form cooperative …

Noncanonical inflammasome activation by intracellular LPS independent of TLR4

N Kayagaki, MT Wong, IB Stowe, SR Ramani… - Science, 2013 - science.org
Gram-negative bacteria including Escherichia coli, Citrobacter rodentium, Salmonella
typhimurium, and Shigella flexneri are sensed in an ill-defined manner by an intracellular …

Fluorescent probes for lipid rafts: from model membranes to living cells

AS Klymchenko, R Kreder - Chemistry & biology, 2014 - cell.com
Membrane microdomains (rafts) remain one of the controversial issues in biophysics.
Fluorescent molecular probes, which make these lipid nanostructures visible through optical …

HOLE: a program for the analysis of the pore dimensions of ion channel structural models

OS Smart, JG Neduvelil, X Wang, BA Wallace… - Journal of molecular …, 1996 - Elsevier
A method (HOLE) that allows the analysis of the dimensions of the pore running through a
structural model of an ion channel is presented. The algorithm uses a Monte Carlo simulated …

Glycopolymer nanobiotechnology

Y Miura, Y Hoshino, H Seto - Chemical reviews, 2016 - ACS Publications
Molecular recognition plays an important role in living systems. 1, 2 Representative
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …

Enabling the'host jump': structural determinants of receptor-binding specificity in influenza A viruses

Y Shi, Y Wu, W Zhang, J Qi, GF Gao - Nature Reviews Microbiology, 2014 - nature.com
The recent emergence of the H7N9 avian influenza A virus and its ability to infect humans
emphasize the epidemic and pandemic potential of these viruses. Interspecies transmission …

[HTML][HTML] Lipid rafts: elusive or illusive?

S Munro - Cell, 2003 - cell.com
There has been considerable recent interest in the possibility that the plasma membrane
contains lipid" rafts," microdomains enriched in cholesterol and sphingolipids. It has been …

MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA

RC Lai, SS Tan, RWY Yeo, ABH Choo… - Journal of …, 2016 - Taylor & Francis
Mesenchymal stem cell (MSC), a widely used adult stem cell candidate for regenerative
medicine, has been shown to exert some of its therapeutic effects through the secretion of …

Self‐assembling organic nanotubes

DT Bong, TD Clark, JR Granja… - Angewandte Chemie …, 2001 - Wiley Online Library
Hollow tubular structures of molecular dimensions perform diverse biological functions in
nature. Examples include scaffolding and packaging roles played by cytoskeletal …