Glycomimetics versus multivalent glycoconjugates for the design of high affinity lectin ligands
One could certainly highlight a conceptual resemblance between social interactions as the
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
basis of societies and civilizations and the ability of molecules to interact in a noncovalent …
Multivalency as a chemical organization and action principle
C Fasting, CA Schalley, M Weber… - Angewandte Chemie …, 2012 - Wiley Online Library
Multivalent interactions can be applied universally for a targeted strengthening of an
interaction between different interfaces or molecules. The binding partners form cooperative …
interaction between different interfaces or molecules. The binding partners form cooperative …
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
N Kayagaki, MT Wong, IB Stowe, SR Ramani… - Science, 2013 - science.org
Gram-negative bacteria including Escherichia coli, Citrobacter rodentium, Salmonella
typhimurium, and Shigella flexneri are sensed in an ill-defined manner by an intracellular …
typhimurium, and Shigella flexneri are sensed in an ill-defined manner by an intracellular …
Fluorescent probes for lipid rafts: from model membranes to living cells
AS Klymchenko, R Kreder - Chemistry & biology, 2014 - cell.com
Membrane microdomains (rafts) remain one of the controversial issues in biophysics.
Fluorescent molecular probes, which make these lipid nanostructures visible through optical …
Fluorescent molecular probes, which make these lipid nanostructures visible through optical …
HOLE: a program for the analysis of the pore dimensions of ion channel structural models
OS Smart, JG Neduvelil, X Wang, BA Wallace… - Journal of molecular …, 1996 - Elsevier
A method (HOLE) that allows the analysis of the dimensions of the pore running through a
structural model of an ion channel is presented. The algorithm uses a Monte Carlo simulated …
structural model of an ion channel is presented. The algorithm uses a Monte Carlo simulated …
Glycopolymer nanobiotechnology
Molecular recognition plays an important role in living systems. 1, 2 Representative
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
molecular recognitions in living organisms are saccharide− protein, protein− protein, and …
Enabling the'host jump': structural determinants of receptor-binding specificity in influenza A viruses
Y Shi, Y Wu, W Zhang, J Qi, GF Gao - Nature Reviews Microbiology, 2014 - nature.com
The recent emergence of the H7N9 avian influenza A virus and its ability to infect humans
emphasize the epidemic and pandemic potential of these viruses. Interspecies transmission …
emphasize the epidemic and pandemic potential of these viruses. Interspecies transmission …
[HTML][HTML] Lipid rafts: elusive or illusive?
S Munro - Cell, 2003 - cell.com
There has been considerable recent interest in the possibility that the plasma membrane
contains lipid" rafts," microdomains enriched in cholesterol and sphingolipids. It has been …
contains lipid" rafts," microdomains enriched in cholesterol and sphingolipids. It has been …
MSC secretes at least 3 EV types each with a unique permutation of membrane lipid, protein and RNA
Mesenchymal stem cell (MSC), a widely used adult stem cell candidate for regenerative
medicine, has been shown to exert some of its therapeutic effects through the secretion of …
medicine, has been shown to exert some of its therapeutic effects through the secretion of …
Self‐assembling organic nanotubes
Hollow tubular structures of molecular dimensions perform diverse biological functions in
nature. Examples include scaffolding and packaging roles played by cytoskeletal …
nature. Examples include scaffolding and packaging roles played by cytoskeletal …