Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: a systematic review

A Romano, TL Rižner, HMJ Werner, A Semczuk… - Frontiers in …, 2023 - frontiersin.org
Endometrial cancer is the most common gynaecological malignancy in developed countries.
Over 382,000 new cases were diagnosed worldwide in 2018, and its incidence and mortality …

A label-free proteomic approach for the identification of biomarkers in the exosome of endometrial cancer serum

E Sommella, V Capaci, M Aloisio, E Salviati… - Cancers, 2022 - mdpi.com
Simple Summary Endometrial cancers (ECs) are mostly adenocarcinomas arising from the
inner part of the uterus. The identification of serum biomarkers may be useful for an early …

Methods and clinical biomarker discovery for targeted proteomics using Olink technology

H Wang, T Zhao, J Zeng, R Zhang, L Pu… - PROTEOMICS …, 2024 - Wiley Online Library
Purpose This paper is to offer insights for designing research utilizing Olink technology to
identify biomarkers and potential therapeutic targets for disease treatment. Experimental …

Fast and reliable Sanger POLE sequencing protocol in FFPE tissues of endometrial cancer

I Laczmanska, D Michalowska, M Jedryka… - … -Research and Practice, 2023 - Elsevier
Background The new classification of endometrial carcinoma (EC) requires molecular
interpretation of somatic polymerase epsilon (POLE) exonuclease domain mutations. The …

A novel device for swift and efficient CD44 protein digestion of pipette tips in human serum

C Rejeeth, NB Varukattu, RS Kumar… - … of Chromatography B, 2023 - Elsevier
For molecular diagnostics in modern biomedical research, electrospray ionisation mass
spectrometry (ESI-MS) based on proteome profiling is important. Now a days, sample …

[HTML][HTML] Translational molecular research has established a novel clinical approach in endometrial cancer patients

M Jędryka - Advances in Clinical and Experimental Medicine, 2023 - advances.umw.edu.pl
Endometrial cancer (EC) is the most common gynecological tumor in developed countries.
Nowadays, molecular biomarkers have become increasingly important in the management …

Immunological and prognostic significance of tumour necrosis in colorectal cancer

M Kastinen, P Sirniö, H Elomaa, M Ahtiainen… - British Journal of …, 2023 - nature.com
Background Colorectal cancer (CRC) causes the second most cancer deaths worldwide, but
the disease course varies according to tumour characteristics and immunological factors …

Molecular markers and endometrial cancer

O D'Oria, G Bogani, E Vizza, V Chiantera… - EUROPEAN …, 2022 - iris.uniroma1.it
Endometrial cancer (EC) is the most common gynecological tumor in industrialized countries
[1, 2]. To date, molecular markers have become increasingly important in the management …