Protein Kinases: Potential Drug Targets Against Schistosoma japonicum

K Wu, X Zhai, S Huang, L Jiang, Z Yu… - Frontiers in Cellular and …, 2021 - frontiersin.org
Schistosoma japonicum (S. japonicum) infection can induce serious organ damage and
cause schistosomiasis japonica which is mainly prevalent in Asia and currently one of the …

Exogenous HMGB1 promotes the proliferation and metastasis of pancreatic cancer cells

L Zhu, S Ren, MJ Daniels, W Qiu, L Song, T You… - Frontiers in …, 2021 - frontiersin.org
Background: Exogenous HMGB1 plays a vital role in tumor recurrence, and HMGB1 is
ubiquitous in the tumor microenvironment. However, the mechanism of action is still unclear …

GSK3β: A ray of hope for the treatment of diabetic kidney disease

LL Liang, MF He, PP Zhou, SK Pan, DW Liu… - The FASEB …, 2024 - Wiley Online Library
Diabetic kidney disease (DKD), a major microvascular complication of diabetes, is
characterized by its complex pathogenesis, high risk of chronic renal failure, and lack of …

Water acidification aggravates lithium-induced toxicity represented by energy supply, oxidative stress, and cell fate in Daphnia magna neonates

Y Zhao, C Duan, Y Xiao, W Gong, Y Wang… - Science of The Total …, 2024 - Elsevier
Lithium is extensively utilized in industrial energy production, particularly in lithium-ion
batteries, and in pharmaceuticals for the treating clinical mood disorders. Consequently …

An RNA Interference Tool to Silence Genes in Sarcoptes scabiei Eggs

DD Fernando, PK Korhonen, RB Gasser… - International Journal of …, 2022 - mdpi.com
In a quest for new interventions against scabies—a highly significant skin disease of
mammals, caused by a parasitic mite Sarcoptes scabiei—we are focusing on finding new …

Molecular cloning, expression and impact of ribosomal protein S-27 silencing in Haemaphysalis longicornis (Acari: Ixodidae)

MK Rahman, B Kim, M You - Experimental parasitology, 2020 - Elsevier
Ticks, obligatory blood-feeding arthropods, are a major pathogen vector in humans and
animals worldwide. Anti-tick vaccines are an exciting alternative to chemical acaricides for …

The hallmarks of GSK-3 in morphogenesis and embryonic development metabolism in arthropods

C Waltero, R Martins, C Calixto, RN da Fonseca… - Insect biochemistry and …, 2020 - Elsevier
Several research groups around the world have studied diverse aspects of energy
metabolism in arthropod disease vectors, with the aim of discovering potential control …

Function of glycogen synthase kinase3 in embryogenesis of Dermanyssus gallinae

J Meng, B Wang, X Qi, P Wang, B Liu, Q Liu, W Sun… - Veterinary …, 2023 - Elsevier
In the life cycle of Dermanyssus gallinae, the embryo is a developmental stage that does not
require blood meals, but needs glucose to produce adenosine triphosphate (ATP) through …

[HTML][HTML] Molecular cloning, identification, transcriptional analysis, and silencing of enolase on the life cycle of Haemaphysalis longicornis (Acari, Ixodidae) tick

MS Haque, MK Rahman, MS Islam… - Parasites, Hosts and …, 2024 - ncbi.nlm.nih.gov
Ticks, blood-sucking ectoparasites, spread diseases to humans and animals.
Haemaphysalis longicornis is a significant vector for tick-borne diseases in medical and …

Molecular characterization of enolase from Haemaphysalis longicornis tick

MS Haque, MK Rahman, MS Islam, M You - bioRxiv, 2022 - biorxiv.org
Enolase is responsible for reversible conversion of D-2-phosphoglycerate and
phosphoenolpyruvate in the glycolysis and gluconeogenesis important for cellular function …