Background A number of protein markers have been investigated as prognostic adjuncts in
breast cancer but their translation into clinical practice has been impeded by a lack of …

There has been no systematic appraisal of ethnicity-based variations in breast cancer (BC)
biology amongst women from developing countries. A qualitative systematic review was …

Experimental evidence suggests that in lung cancer, development, progression and an
increased proliferation rate can be linked to apoptosis-related factors. The objective of this …

Aims: The purpose of this study was to determine if any relationship exists between Estrogen
Receptor (ER), Progesterone Receptor (PR), Her2/neu, P53, and clinicopathological factors …

Background: A significant development in the breast carcinoma management is the
correlation between the presence of hormone receptors in the tumor and response to …

Abstract p53 wild-type is a tumor suppressor gene involved in DNA gene transcription or
DNA repair mechanisms. When damage to DNA is unrepairable, p53 induces programmed …

Background Inactivation or mutation of the tumour suppressor gene p53 or its regulator
mouse double minute 2 (MDM2) is the commonest event in breast cancer. These altered …

Background Breast cancer (BC) is one of the most common malignancies and a foremost
health issue throughout world. BC accounted for 23.1% of cancer cases diagnosed in Oman …

The study was done over a period of 10 years, 1996–2005 and it included 562 mammary
cancer patients. Of the 562 cases, 100 cases of invasive mammary carcinoma included in …

Aim: HER2/neu protein has garnered a great deal of interest in the popular media. However,
it has long been known among pathologists and oncologists for its potential role as a tumor …