Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds

X Yu, P Liu, Z Li, Z Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

Human cells with osteogenic potential in bone tissue research

J Dvorakova, L Wiesnerova, P Chocholata… - BioMedical Engineering …, 2023 - Springer
Bone regeneration after injury or after surgical bone removal due to disease is a serious
medical challenge. A variety of materials are being tested to replace a missing bone or tooth …

[HTML][HTML] Human urine-derived stem cells protect against renal ischemia/reperfusion injury in a rat model via exosomal miR-146a-5p which targets IRAK1

X Li, J Liao, X Su, W Li, Z Bi, J Wang, Q Su, H Huang… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI) that
is associated with high morbidity and mortality, and for which specific treatments are lacking …

Research progress on toxicity, function, and mechanism of metal oxide nanoparticles on vascular endothelial cells

Z Wang, M Tang - Journal of Applied Toxicology, 2021 - Wiley Online Library
Metal oxide nanoparticles present stable and unique performance that makes them suitable
for various biomedical applications. There are four common exposure ways that …

Body fluid-derived stem cells—an untapped stem cell source in genitourinary regeneration

RL Huang, Q Li, JX Ma, A Atala, Y Zhang - Nature Reviews Urology, 2023 - nature.com
Somatic stem cells have been obtained from solid organs and tissues, including the bone
marrow, placenta, corneal stroma, periosteum, adipose tissue, dental pulp and skeletal …

SHED promote angiogenesis in stem cell-mediated dental pulp regeneration

H Guo, W Zhao, A Liu, M Wu, Y Shuai, B Li… - Biochemical and …, 2020 - Elsevier
Dental pulp, plays an indispensable role in maintaining homeostasis of the tooth. Pulp
necrosis always causes tooth nutrition deficiency and abnormal root development, which …

Drug-induced nephrotoxicity assessment in 3D cellular models

P Yu, Z Duan, S Liu, I Pachon, J Ma, GP Hemstreet… - Micromachines, 2021 - mdpi.com
The kidneys are often involved in adverse effects and toxicity caused by exposure to foreign
compounds, chemicals, and drugs. Early predictions of these influences are essential to …

Hypoxic preconditioning of human urine-derived stem cell-laden small intestinal submucosa enhances wound healing potential

XR Zhang, YZ Huang, HW Gao, YL Jiang… - Stem Cell Research & …, 2020 - Springer
Background Urine-derived stem cells (USCs) are a valuable stem cell source for tissue
engineering because they can be harvested non-invasively. Small intestine submucosa …

Extracellular matrix derived from human urine-derived stem cells enhances the expansion, adhesion, spreading, and differentiation of human periodontal ligament …

X Xiong, X Yang, H Dai, G Feng, Y Zhang… - Stem cell research & …, 2019 - Springer
Background Human periodontal ligament stem cells (hPDLSCs) are one of the most
promising types of seed cells in periodontal tissue regeneration. Suitable biomaterials are …

A cocktail of growth factors released from a heparin hyaluronic-acid hydrogel promotes the myogenic potential of human urine-derived stem cells in vivo

G Liu, R Wu, B Yang, Y Shi, C Deng, A Atala, S Mou… - Acta biomaterialia, 2020 - Elsevier
Traditional cell therapy technology relies on the maximum expansion of primary stem cells in
vitro, through multiple passages and potential differentiation protocols, in order to generate …