Recent advances in genetic systems in obligate intracellular human-pathogenic bacteria

DJ Fisher, PA Beare - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
The ability to genetically manipulate a pathogen is fundamental to discovering factors
governing host–pathogen interactions at the molecular level and is critical for devising …

Evolutionary insights into the tick hologenome

S Díaz-Sánchez, A Estrada-Peña, A Cabezas-Cruz… - Trends in …, 2019 - cell.com
Recently, our knowledge of the composition and complexity of tick microbial communities
has increased and supports microbial impact on tick biology. Results support a phylogenetic …

[HTML][HTML] The Tick Cell Biobank: A global resource for in vitro research on ticks, other arthropods and the pathogens they transmit

L Bell-Sakyi, A Darby, M Baylis… - Ticks and tick-borne …, 2018 - Elsevier
Tick cell lines are increasingly used in many fields of tick and tick-borne disease research.
The Tick Cell Biobank was established in 2009 to facilitate the development and uptake of …

Cryptic Genes for Interbacterial Antagonism Distinguish Rickettsia Species Infecting Blacklegged Ticks From Other Rickettsia Pathogens

VI Verhoeve, TD Fauntleroy, RG Risteen… - Frontiers in cellular …, 2022 - frontiersin.org
Background The genus Rickettsia (Alphaproteobacteria: Rickettsiales) encompasses
numerous obligate intracellular species with predominantly ciliate and arthropod hosts …

What do we know about the microbiome of I. ricinus?

R Hodosi, M Kazimirova, K Soltys - Frontiers in cellular and infection …, 2022 - frontiersin.org
I. ricinus is an obligate hematophagous parasitic arthropod that is responsible for the
transmission of a wide range of zoonotic pathogens including spirochetes of the genus …

Tick extracellular vesicles in host skin immunity and pathogen transmission

LR Butler, J Gonzalez, JHF Pedra, ASO Chavez - Trends in Parasitology, 2023 - cell.com
Ticks can transmit a variety of human pathogens, including intracellular and extracellular
bacteria, viruses, and protozoan parasites. Historically, their saliva has been of immense …

Recent advances in understanding tick and rickettsiae interactions

S Karim, D Kumar, K Budachetri - Parasite immunology, 2021 - Wiley Online Library
Ticks are haematophagous arthropods with unique molecular mechanisms for digesting
host blood meal while acting as vectors for various pathogens of public health significance …

Tick humoral responses: marching to the beat of a different drummer

AS Oliva Chávez, DK Shaw, UG Munderloh… - Frontiers in …, 2017 - frontiersin.org
Ticks transmit a variety of human pathogens, including Borrelia burgdorferi, the etiological
agent of Lyme disease. Multiple pathogens that are transmitted simultaneously, termed …

Isolation and Propagation of Laboratory Strains and a Novel Flea-Derived Field Strain of Wolbachia in Tick Cell Lines

JJ Khoo, TJ Kurtti, NA Husin, A Beliavskaia, FS Lim… - Microorganisms, 2020 - mdpi.com
Wolbachia are intracellular endosymbionts of several invertebrate taxa, including insects
and nematodes. Although Wolbachia DNA has been detected in ticks, its presence is …

Multiple Ehrlichia chaffeensis Genes Critical for Its Persistent Infection in a Vertebrate Host Are Identified by Random Mutagenesis Coupled with In Vivo Infection …

Y Wang, ADS Nair, A Alhassan, DC Jaworski… - Infection and …, 2020 - Am Soc Microbiol
Ehrlichia chaffeensis, a tick-transmitted obligate intracellular rickettsial agent, causes human
monocytic ehrlichiosis. In recent reports, we described substantial advances in developing …