Monoclonal antibodies (mAbs) have become one of the most important classes of
biopharmaceutical products, and they continue to dominate the universe of …

With the development of radiotherapeutic oncology, computer technology and medical
imaging technology, radiation therapy has made great progress. Research on the impact …

Background Non-small cell lung cancer (NSCLC) cells derived intracellular and extracellular
programmed cell death ligand 1 (PD-L1) promoted cancer progression and drug resistance …

Blockade of PD-L1 expression on tumor cells via anti–PD-L1 monoclonal antibody (mAb)
has shown great promise for successful cancer treatment by overcoming T-cell exhaustion; …

Site-selective acetylation of a single lysine residue in a protein that reaches a lysine
acetyltransferase's accuracy, precision, and reliability is challenging. Here, we report a …

Background The chimeric antigen receptor NK‐92 (CAR NK‐92) cell targeting the prostate‐
specific membrane antigen (PSMA) has shown antitumour effects in castration‐resistant …

Despite improved methods of diagnosis and the development of different treatments,
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …

Immunotherapy targeting checkpoint blockade to rescue T cells from exhaustion has
become an essential therapeutic strategy in treating cancers. Till now, little is known about …

Lung cancer is the leading cause of cancer deaths worldwide, mainly because it is usually in
the advanced stage at the time of diagnosis. Although great progress has been made in the …

Objective: Patient-derived xenograft (PDX) models have shown great promise in preclinical
and translational applications, but their consistency with primary tumors in phenotypic …