Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

In biology, it can be argued that if the genome contains the script for a cell's life cycle, then
the proteome constitutes an ensemble cast of actors that brings these instructions to life …

Native mass spectrometry (MS) has become widely accepted in structural biology, providing
information on stoichiometry, interactions, homogeneity, and shape of protein complexes …

Cross-linking mass spectrometry (XL-MS) has received considerable interest, owing to its
potential to investigate protein–protein interactions (PPIs) in an unbiased fashion in complex …

INTRODUCTION Circadian clocks provide an internal representation of local time inside
cells and control the timing of gene expression in anticipation of sunrise and sunset. In …

For the last century we have relied on model organisms to help understand fundamental
biological processes. Now, with advancements in genome sequencing, assembly, and …

Protein interactions underlie most molecular events in biology. Many methods have been
developed to identify protein partners, to measure the affinity with which these biomolecules …

The design of new therapeutic molecules can be significantly informed by studying protein-
ligand interactions using biophysical approaches directly after purification of the protein …

Oscillation is an intriguing phenomenon in nature. However, structural oscillation has not yet
been found in semiconducting nanoparticles, primarily due to the difficulty of structural …

Combining diverse experimental structural and interactomic methods allows for the
construction of comprehensible molecular encyclopedias of biological systems. Typically …