The continued threat of emerging flaviviruses
TC Pierson, MS Diamond - Nature microbiology, 2020 - nature.com
Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …
populations and cause a spectrum of potentially severe diseases including hepatitis …
Dengue: a minireview
Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a
mosquito-borne disease of major public health concern associated with significant morbidity …
mosquito-borne disease of major public health concern associated with significant morbidity …
Current understanding of the pathogenesis of dengue virus infection
The pathogenesis of dengue virus infection is attributed to complex interplay between virus,
host genes and host immune response. Host factors such as antibody-dependent …
host genes and host immune response. Host factors such as antibody-dependent …
[HTML][HTML] Dengue overview: An updated systemic review
Dengue is caused by the dengue virus (DENVs) infection and clinical manifestations include
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …
dengue fever (DF), dengue hemorrhagic fever (DHF), or dengue shock syndrome (DSS) …
Evolutionary enhancement of Zika virus infectivity in Aedes aegypti mosquitoes
Zika virus (ZIKV) remained obscure until the recent explosive outbreaks in French Polynesia
(2013–2014) and South America (2015–2016),,. Phylogenetic studies have shown that ZIKV …
(2013–2014) and South America (2015–2016),,. Phylogenetic studies have shown that ZIKV …
Dengue virus NS1 triggers endothelial permeability and vascular leak that is prevented by NS1 vaccination
PR Beatty, H Puerta-Guardo, SS Killingbeck… - Science translational …, 2015 - science.org
The four dengue virus serotypes (DENV1 to DENV4) are mosquito-borne flaviviruses that
cause up to~ 100 million cases of dengue annually worldwide. Severe disease is thought to …
cause up to~ 100 million cases of dengue annually worldwide. Severe disease is thought to …
West Nile virus: an update on pathobiology, epidemiology, diagnostics, control and “one health” implications
West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe,
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …
lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its …
Flavivirus NS1 triggers tissue-specific vascular endothelial dysfunction reflecting disease tropism
Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus
nonstructural protein 1 (NS1) is a secreted glycoprotein involved in viral replication, immune …
nonstructural protein 1 (NS1) is a secreted glycoprotein involved in viral replication, immune …
An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
Virus–host interactions determine an infection outcome. The Asian lineage of Zika virus
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
(ZIKV), responsible for the recent epidemics, has fixed a mutation in the NS1 gene after …
A rhesus macaque model of Asian-lineage Zika virus infection
DM Dudley, MT Aliota, EL Mohr, AM Weiler… - Nature …, 2016 - nature.com
Abstract Infection with Asian-lineage Zika virus (ZIKV) has been associated with Guillain–
Barré syndrome and fetal abnormalities, but the underlying mechanisms remain poorly …
Barré syndrome and fetal abnormalities, but the underlying mechanisms remain poorly …