Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are suggested to be
responsible for drug resistance and cancer relapse due in part to their ability to self‐renew …

High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Glioblastoma is the most common and lethal primary malignant brain tumor in adults.
Patients die from recurrent tumors that have become resistant to therapy. New strategies are …

Glioblastoma (GBM) is one of the most aggressive and lethal human brain tumors. At
present, GBMs are divided in primary and secondary on the basis of the mutational status of …

Glioblastomas are lethal cancers defined by angiogenesis and pseudopalisading necrosis.
Here, we demonstrate that these histological features are associated with distinct …

microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …

Epigenetic regulation of gene expression is an increasingly well-understood concept that
explains much of the contribution of an organism's environment and experience to its …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

The use of small interfering RNAs (siRNAs) to induce gene silencing has opened a new
avenue in drug discovery. However, their therapeutic potential is hampered by inadequate …