Our increased understanding of how key metabolic pathways are activated and regulated in
malignant cells has identified metabolic vulnerabilities of cancers. Translating this insight to …

Acid-sensing ion channel 1a (ASIC1a), a prominent member of the acid-sensing ion channel
(ASIC) superfamily activated by extracellular protons, is ubiquitously expressed throughout …

The mystery about the mechanistic basis of disulfidptosis has recently been unraveled and
shows promise as an effective treatment modality for triggering cancer cell death. However …

Immunotherapy exhibited potential effects for advanced hepatocellular carcinoma,
unfortunately, the clinical benefits are often countered by cancer adaptive immune …

The broad effectiveness of T cell-based therapy for treating solid tumour cancers remains
limited. This is partly due to the growing appreciation that immune cells must inhabit and …

Simple Summary Localized renal cell carcinoma (RCC) has an excellent prognosis.
However, once metastatic, patient prognosis declines significantly. There is a rare patient …

Abstract Calcium ions (Ca 2+) are crucial in tumorigenesis and progression, with their
elevated levels indicating a negative prognosis in Kidney Renal Clear Cell Carcinoma …

Comprehensively studying metabolism requires the measurement of metabolite levels.
However, in contrast to the broad availability of gene expression data, metabolites are rarely …