Radiogenomics in renal cancer management—current evidence and future prospects

M Ferro, G Musi, M Marchioni, M Maggi… - International journal of …, 2023 - mdpi.com
Renal cancer management is challenging from diagnosis to treatment and follow-up. In
cases of small renal masses and cystic lesions the differential diagnosis of benign or …

Novel imaging methods for renal mass characterization: a collaborative review

E Roussel, U Capitanio, A Kutikov, E Oosterwijk… - European urology, 2022 - Elsevier
Context The incidental detection of localized renal masses has been rising steadily, but a
significant proportion of these tumors are benign or indolent and, in most cases, do not …

Phase II study of neoadjuvant nivolumab in patients with locally advanced clear cell renal cell carcinoma undergoing nephrectomy

MI Carlo, K Attalla, Y Mazaheri, S Gupta, O Yildirim… - European urology, 2022 - Elsevier
Immune checkpoint inhibitor therapy improves survival in patients with metastatic renal cell
carcinoma (RCC) but has not been studied well preoperatively in patients with localized …

Deep learning can predict survival directly from histology in clear cell renal cell carcinoma

F Wessels, M Schmitt, E Krieghoff-Henning, JN Kather… - PLoS …, 2022 - journals.plos.org
For clear cell renal cell carcinoma (ccRCC) risk-dependent diagnostic and therapeutic
algorithms are routinely implemented in clinical practice. Artificial intelligence-based image …

Biomarkers for renal cell carcinoma recurrence: state of the art

M Marchioni, JG Rivas, A Autran, M Socarras… - Current Urology …, 2021 - Springer
Abstract Purpose of Review We aim to summarize the current state of art about the possible
use of biomarkers for predicting renal cell carcinoma (RCC) recurrence after curative …

Cell competition shapes metastatic latency and relapse

K Kim, H Huang, PK Parida, L He, M Marquez-Palencia… - Cancer discovery, 2023 - AACR
Cell competition, a fitness-sensing process, is essential for tissue homeostasis. Using
cancer metastatic latency models, we show that cell competition results in the displacement …

Real-world survival outcomes associated with first-line immunotherapy, targeted therapy, and combination therapy for metastatic clear cell renal cell carcinoma

NH Chakiryan, DD Jiang, KA Gillis, E Green… - JAMA Network …, 2021 - jamanetwork.com
Importance Clinical trials have shown an overall survival (OS) benefit associated with first-
line immunotherapy (IT) and combination targeted therapy (TT) and IT regimens compared …

Role of clinicopathological variables in predicting recurrence and survival outcomes after surgery for non‐metastatic renal cell carcinoma: Systematic review and meta …

M Majdoub, T Yanagisawa, F Quhal… - … Journal of Cancer, 2024 - Wiley Online Library
Renal cell carcinoma (RCC) represents 2% of all diagnosed malignancies worldwide, with
disease recurrence affecting 20% to 40% of patients. Existing prognostic recurrence models …

Tumor stage and substage predict cancer-specific mortality after nephrectomy for nonmetastatic renal cancer: histological subtype-specific validation

L Nocera, CC Ruvolo, LF Stolzenbach, M Wenzel… - European urology …, 2022 - Elsevier
Background For patients with nonmetastatic renal cell carcinoma (nmRCC) treated with
nephrectomy, prediction of cancer-specific mortality (CSM) by T stage and substage has not …

Machine learning-based prediction model for late recurrence after surgery in patients with renal cell carcinoma

HM Kim, SS Byun, JK Kim, CW Jeong, C Kwak… - BMC Medical Informatics …, 2022 - Springer
Background Renal cell carcinoma is characterized by a late recurrence that occurs 5 years
after surgery; hence, continuous monitoring and follow-up is necessary. Prognosis of late …