[HTML][HTML] Differential expression of miRNAs contributes to tumor aggressiveness and racial disparity in African American men with prostate cancer

R Ottman, K Ganapathy, HY Lin, CD Osterman, J Dutil… - Cancers, 2023 - mdpi.com
Simple Summary Prostate cancer (PCa) is the leading cancer in incidence and second
leading cause of cancer mortality in US men. Recent data showed a 3% increase in PCa …

Revealing metastatic castration‐resistant prostate cancer master regulator through lncRNAs‐centered regulatory network

RS Ferraz, JVF Cavalcante, L Magalhães… - Cancer …, 2023 - Wiley Online Library
Background Metastatic castration‐resistant prostate cancer (mCRPC) is an aggressive form
of cancer unresponsive to androgen deprivation therapy (ADT) that spreads quickly to other …

[HTML][HTML] Identification of F-Box/SPRY Domain-Containing Protein 1 (FBXO45) as a Prognostic Biomarker for TMPRSS2–ERG-Positive Primary Prostate Cancers

M von Danwitz, N Klümper, M Bernhardt, A Cox… - Cancers, 2023 - mdpi.com
Simple Summary FBXO45 plays a role in the regulation of apoptosis through the
ubiquitylation and degradation of specific target proteins. While FBXO45 has been …

Influence of radical prostatectomy on miRNA dynamics in urine extracellular vesicles

EV Shutko, OE Bryzgunova, EA Murina… - … Oncology: Seminars and …, 2024 - Elsevier
Purpose Cancer statistics demonstrate leading growth of prostate cancer. As a rule, radical
prostatectomy (RP) is a mandatory option in the treatment of localized prostate cancer …

[HTML][HTML] Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Qizhu prescription for treating breast cancer

J Sheng, J Cheng, W Chu, M Dong, K Jiang - Journal of Traditional Chinese …, 2024 - Elsevier
Objective To investigate the mechanism underlying the effects exerted by the Qizhu
prescription (QZP) in breast cancer (BC), and the respective targets. Methods Expression …

Epigenetic regulation of androgen dependent and independent prostate cancer

J Mishra, S Chakraborty, P Nandi… - … in cancer research, 2024 - pubmed.ncbi.nlm.nih.gov
Prostate cancer is one of the most common malignancies among men worldwide. Besides
genetic alterations, epigenetic modulations including DNA methylation, histone …

Investigation of miR-15b-5p expression and role in head and neck squamous cell carcinoma based on meta-analysis and bioinformatics analysis

X Su, Z Zhou, W Chen, M Zhu, L Wu, Y Yin, S Chen… - 2023 - researchsquare.com
Background: In the current study, miR-15b-5p expression and role in HNSCC remains
indistinct. The aim of this study was to investigate the expression and role of miR-15b-5p in …

Biological function analysis of miR-15b-5p promoting head and neck tumor development by targeting UGT1A7

X Su, Z Zhou, W Chen, M Zhu, L Wu, Y Yin, S Chen… - 2023 - researchsquare.com
Background: Head and neck squamous cell carcinoma (HNSCC) is a common malignant
tumor. MicroRNA function and expression abnormalities are closely related to tumor …