Background Clear cell renal cell carcinoma (ccRCC) is a common genitourinary cancer type
with a high mortality rate. Due to a diverse range of biochemical alterations and a high level …

Simple Summary DNA information can be copied into mRNA (this process is called
transcription) and proteins can be subsequently synthesized using the information in mRNA …

Background Quaking (QKI) is a member of the signal transduction and activators of RNA
(STAR) family, performing a crucial multifunctional regulatory role in alternative splicing …

The aim of this article was to construct an accurate prognostic model using RNA-binding
proteins (RBPs) to predict overall survival (OS) for patients with clear cell renal cell …

Splicing factors (SFs) are the major RNA-binding proteins (RBPs) and key molecules that
regulate the splicing of mRNA molecules through binding to mRNAs. The expression of …

Identification of driver genes, whose mutations cause the development of tumors, is crucial
for the improvement of cancer research and precision medicine. To overcome the problem …

Aberrant alternative splicing (AS) is increasingly linked to cancer; however, how AS
contributes to cancer development still remains largely unknown. AS events (ASEs) are …

Background Alternative splicing (AS) is a critical mechanism of post-transcriptional
regulation and has been widely reported to be associated with the tumor progression and …

RNA-seq analysis of alternative pre-mRNA splicing has facilitated an unprecedented
understanding of transcriptome complexity in health and disease. However, despite the …

RNA-binding proteins (RBPs) are integral components of cellular machinery, playing crucial
roles in the regulation of gene expression and maintaining genetic stability. Their …