Fibrosis is characterized by the excessive extracellular matrix deposition due to
dysregulated wound and connective tissue repair response. Multiple organs can develop …

The peroxisome proliferator-activated receptors (PPAR-α, PPAR-β/δ, and PPAR-γ) are
members of the nuclear receptor super-family, acting as ligand-inducible transcription …

Peroxisome proliferator-activated receptor α (PPARα) is a ligand-activated transcription
factor that is involved in lipid metabolism of various tissues. Different metabolites of fatty …

Background Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis
(NASH) have become significant global health concerns. In the present study, we aimed to …

Highlights•NAFLD is highly prevalent and affects at least one-third of the global
population.•Currently, there is no drug to cure NAFLD.•Fenofibrate is a PPARα agonist with …

Nonalcoholic fatty liver disease (NAFLD) is initiated by excessive fat buildup in the liver,
affecting around 35% of the world population. Various circumstances contribute to the …

Background: Peroxisome proliferator-activated receptor gamma (PPARγ) is a member of the
nuclear receptor superfamily of ligand-inducible transcription factors that regulate …

The most epidemic liver disorder non-alcoholic steatohepatitis (NASH) is characterized by
hepatic steatosis and inflammation with hepatocellular damage. Recently, it is predictable to …

Aim The neuronal damage and accompanied functional deficits induced by cerebral
ischemia are among the most common causes of disabilities in adults. Activation of subtypes …

Results According to the results of this study, 90 patients with NAFLD were divided into three
groups of 30 patients. All variables at the beginning of the study showed no significant …