From conventional to precision therapy in canine mammary cancer: a comprehensive review

G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

Biomarkers in breast cancer: an old story with a new end

L Neves Rebello Alves, D Dummer Meira… - Genes, 2023 - mdpi.com
Breast cancer is the second most frequent cancer in the world. It is a heterogeneous disease
and the leading cause of cancer mortality in women. Advances in molecular technologies …

A subset of activated fibroblasts is associated with distant relapse in early luminal breast cancer

C Bonneau, A Eliès, Y Kieffer, B Bourachot… - Breast Cancer …, 2020 - Springer
Background Early luminal breast cancer (BC) represents 70% of newly diagnosed BC
cases. Among them, small (under 2 cm) BC without lymph node metastasis (classified as …

[HTML][HTML] Potential molecular mechanisms and clinical progress in liver metastasis of breast cancer

H Liu, X Li, H Li, L Feng, G Sun, G Sun, L Wu… - Biomedicine & …, 2022 - Elsevier
Breast cancer is the most common malignant tumor in women and the leading cause of
cancer death in women. About 30% of breast cancer patients have metastasis every year …

CDH1 germline mutations in families with hereditary lobular breast cancer

A Girardi, F Magnoni, E Vicini, A Kouloura… - European Journal of …, 2022 - journals.lww.com
Pathogenic CDH1 germline mutations are associated with lobular breast cancer in the so-
called hereditary lobular breast cancer (HLBC) syndrome, without apparent correlation with …

lncRNA CRNDE Affects Th17/IL‐17A and Inhibits Epithelial‐Mesenchymal Transition in Lung Epithelial Cells Reducing Asthma Signs

Y Yuan, Y He, B Wasti, W Duan, J Jia… - Oxidative Medicine …, 2023 - Wiley Online Library
Background. Asthma treatment is difficult due to disease heterogeneity and comorbidities. In
addition, the development of drugs targeting the underlying mechanisms of asthma remains …

Association of quantitative analysis of intratumoral reduced E-cadherin expression with lymph node metastasis and prognosis in patients with breast cancer

X Meng, M Morita, S Kuba, H Hayashi, R Otsubo… - Scientific Reports, 2023 - nature.com
Loss of E-cadherin expression is a poor prognostic factor in patients with breast cancer.
Breast cancer cells co-cultured with adipocytes reportedly promote E-cadherin attenuation …

Aberrations of chromosomes 1 and 16 in breast cancer: a framework for cooperation of transcriptionally dysregulated genes

AP Privitera, V Barresi, DF Condorelli - Cancers, 2021 - mdpi.com
Simple Summary Classical cytogenetic studies in breast cancer have identified frequent
chromosomal aberrations that produce an increased gene copy number in chromosome 1q …

[HTML][HTML] Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling

EF Cromwell, O Sirenko, E Nikolov, M Hammer… - SLAS Discovery, 2022 - Elsevier
Abstract 3D cell models derived from patient tumors are highly translational tools that can
recapitulate the complex genetic and molecular compositions of solid cancers and …

Calcium-Mediated Cell Adhesion Enhancement-Based Antimetastasis and Synergistic Antitumor Therapy by Conjugated Polymer–Calcium Composite Nanoparticles

J He, Y Wang, Y Ren, Q Yuan, Z Zhang, L Li, B Bao… - ACS …, 2024 - ACS Publications
Strengthening tumor cellular adhesion through regulating the concentration of extracellular
Ca2+ is highly challenging and promising for antimetastasis. Herein, a pH-responsive …