NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

The blood–brain barrier (BBB) is the interface between the central nervous system and
systemic circulation. It tightly regulates what enters and is removed from the brain …

Labeling in diffusion measurements by pulsed field gradient (PFG) NMR is based on the
observation of the phase of nuclear spins acquired in a constant magnetic field with …

Diffusion encoding along multiple spatial directions per signal acquisition can be described
in terms of a b-tensor. The benefit of tensor-valued diffusion encoding is that it unlocks …

The blood-brain barrier (BBB) regulates the transfer of solutes and essential nutrients into
the brain. Growing evidence supports BBB dysfunction in a range of acute and chronic brain …

Despite their widespread use in non-invasive studies of porous materials, conventional MRI
methods yield ambiguous results for microscopically heterogeneous materials such as brain …

Imaging is an indispensable tool for brain tumour diagnosis, surgical planning, and follow-
up. Definite diagnosis, however, often demands histopathological analysis of microscopic …

The exchange of molecules between different physical or chemical environments due to
diffusion or chemical transformations has a crucial role in a plethora of fundamental …

Purpose To evaluate potential modeling paradigms and the impact of relaxation time effects
on human blood‐brain barrier (BBB) water exchange measurements using FEXI (BBB …

For its size, the brain is the most metabolically active organ in the body. Most of its energy
demand is used to maintain stable homeostatic physiological conditions. Altered …