Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

Abstract The dysregulation of N (7)-methylguanosine (m7G) modification is increasingly
recognized as a key factor in the pathogenesis of cancers. Aberrant expression of these …

N-7methylguanosine (m7G) modification plays a crucial role in various biological processes
and is closely associated with the development and progression of many cancers. Accurate …

Abstract We present Sci-ModoM, the first next-generation RNome database offering a
holistic view of the epitranscriptomic landscape. Sci-ModoM has a simple yet powerful …

Senescence is the underlying mechanism of organism aging and is robustly regulated at the
post-transcriptional level. This regulation involves the chemical modifications, of which the …

Liquid–liquid phase separation (LLPS) is a crucial process for the formation of biomolecular
condensates such as coacervate droplets, P-bodies and stress granules, which play critical …

Cancer is a complex and multifaceted group of diseases characterized by uncontrolled cell
growth that leads to the formation of malignant tumors. Recent studies suggest that N6 …

The discovery of N6-methyladenosine (m 6 A) methylation and its role in translation has led
to the emergence of a new field of research. Despite accumulating evidence suggesting that …

Abstract N6-methyladenosine (m 6 A) is a highly prevalent and conserved post-
transcriptional modification observed in mRNA and long non-coding RNA (lncRNA) …

formylcytidine (f 5 C) is a unique post-transcriptional RNA modification found in mRNA and
tRNA at the wobble site, playing a crucial role in mitochondrial protein synthesis and …