Recent progress on the stereoselective synthesis of cyclic quaternary α-amino acids

C Cativiela, M Ordóñez - Tetrahedron: Asymmetry, 2009 - Elsevier
The most recent papers describing the stereoselective synthesis of cyclic quaternary α-
amino acids are collected in this review. The diverse synthetic approaches are classified …

Dehydroamino acids: Chemical multi-tools for late-stage diversification

JW Bogart, AA Bowers - Organic & biomolecular chemistry, 2019 - pubs.rsc.org
α, β-Dehydroamino acids (dhAAs) are noncanonical amino acids that are found in a wide
array of natural products and can be easily installed into peptides and proteins. dhAAs …

Total synthesis of the thiopeptide antibiotic amythiamicin D

RA Hughes, SP Thompson, L Alcaraz… - Journal of the American …, 2005 - ACS Publications
The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified
cyclic peptides with interesting biological properties, including reported activity against …

An evaluation of amide group planarity in 7-azabicyclo [2.2. 1] heptane amides. Low amide bond rotation barrier in solution

Y Otani, O Nagae, Y Naruse, S Inagaki… - Journal of the …, 2003 - ACS Publications
Here we show that amides of bicyclic 7-azabicyclo [2.2. 1] heptane are intrinsically nitrogen-
pyramidal. Single-crystal X-ray diffraction structures of some relevant bicyclic amides …

[图书][B] Practical synthetic organic chemistry: reactions, principles, and techniques

S Caron - 2020 - books.google.com
Diese Publikation ist ein Praktikerbuch für Organiker. Der Schwerpunkt liegt auf den
Reaktionen, die am verlässlichsten und nützlichsten sind. Die Autoren der einzelnen Kapitel …

A compendium of cyclic sugar amino acids and their carbocyclic and heterocyclic nitrogen analogues

M Risseeuw, M Overhand, GWJ Fleet, MI Simone - Amino acids, 2013 - Springer
This compendium focuses on functionalised sugar amino acids (SAAs) and their 3-to 6-
membered nitrogen heterocyclic and carbocyclic analogues. The main benefit of using SAAs …

Stereoretentive formation of cyclobutanes from pyrrolidines: lessons learned from DFT studies of the reaction mechanism

R Monreal-Corona, M Solà… - The Journal of …, 2023 - ACS Publications
The stereoselective synthesis of cyclobutanes that possess an array of stereocenters in a
contiguous fashion has attracted the wide interest of the synthetic community. Cyclobutanes …

α, β-Dehydroamino Acids

C Bonauer, T Walenzyk, B König - Synthesis, 2006 - thieme-connect.com
Dehydroamino acids are versatile intermediates in organic synthesis and occur as frequent
structural motives in natural products and biologically active compounds. This review …

Conformationally rigid cyclic α-amino acids in the design of peptidomimetics, peptide models and biologically active compounds

IV Komarov, AO Grigorenko, AV Turov… - Russian chemical …, 2004 - pubs.rsc.org
A class of conformationally rigid cyclic α-amino acids that can be used in the synthesis of
peptidomimetics, peptide models and biologically active compounds is surveyed. The rigid …

Discovery of a Novel, Highly Potent, and Selective Thieno[3,2-d]pyrimidinone-Based Cdc7 Inhibitor with a Quinuclidine Moiety (TAK-931) as an Orally Active …

O Kurasawa, T Miyazaki, M Homma… - Journal of Medicinal …, 2020 - ACS Publications
In our pursuit of developing a novel, potent, and selective cell division cycle 7 (Cdc7)
inhibitor, we optimized the previously reported thieno [3, 2-d] pyrimidinone analogue I …