CHIPing away the progression potential of CHIP: a new reality in the making

Z Xie, AM Zeidan - Blood Reviews, 2023 - Elsevier
Over the past few years, we have gained a deeper understanding of clonal hematopoiesis of
indeterminate potential (CHIP), especially with regard to the epidemiology, clinical …

Clinical implications and genetic features of clonal cytopenia of undetermined significance compared to lower‐risk myelodysplastic syndrome

EJ Choi, YU Cho, EH Hur, HS Park… - British Journal of …, 2022 - Wiley Online Library
Clonal cytopenia of undetermined significance (CCUS) is characterized by persistent
cytopenias with genetic aberrations, which do not meet the diagnostic criteria for …

Premalignant Clonal Hematopoiesis (Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance)

KE Craven, MD Ewalt - Clinics in Laboratory Medicine, 2023 - labmed.theclinics.com
Clonal hematopoiesis (CH) is the presence of somatic alterations in the peripheral blood of
individuals without evidence of a hematologic malignancy. 1–4 When these alterations are …

Clonal hematopoiesis in unexplained cytopenias

H Wu, C Gu, S Liu, Q Dong, L Dong… - American journal …, 2023 - pubmed.ncbi.nlm.nih.gov
Clonal hematopoiesis in unexplained cytopenias Clonal hematopoiesis in unexplained
cytopenias Am J Hematol. 2023 Dec;98(12):E407-E410. doi: 10.1002/ajh.27120. Epub 2023 …

SOHO state of the art updates and next questions: treatment of lower risk myelodysplastic syndromes

VO Volpe, G Garcia-Manero, RS Komrokji - Clinical Lymphoma Myeloma …, 2023 - Elsevier
MDS is a clonal stem cell neoplasm with a spectrum from lower risk disease to short term life
threatening higher risk disease. The disease risk is dictated by clinical and molecular …

Blood count abnormalities and evolution of clonal hematopoiesis

I van Zeventer - 2024 - research.rug.nl
Somatic mutations accumulate in hematopoietic stem or progenitor cells with advancing age
and may confer a selective growth advantage resulting in clonal expansion. So-called clonal …