Sex matters: a comprehensive comparison of female and male hearts
Cardiovascular disease in women remains under-diagnosed and under-treated. Recent
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …
studies suggest that this is caused, at least in part, by the lack of sex-specific diagnostic …
Sex and gender differences in myocarditis and dilated cardiomyopathy: an update
DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …
[HTML][HTML] hERG K+ channels: structure, function, and clinical significance
The human ether-a-go-go related gene (hERG) encodes the pore-forming subunit of the
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …
rapid component of the delayed rectifier K+ channel, Kv11. 1, which are expressed in the …
Basic notions of heart rate variability and its clinical applicability
Autonomic nervous system (ANS) plays an important role in the regulation of the
physiological processes of the human organism during normal and pathological conditions …
physiological processes of the human organism during normal and pathological conditions …
[HTML][HTML] Noções básicas de variabilidade da frequência cardíaca e sua aplicabilidade clínica
O sistema nervoso autônomo (SNA) desempenha um papel importante na regulação dos
processos fisiológicos do organismo humano tanto em condições normais quanto …
processos fisiológicos do organismo humano tanto em condições normais quanto …
The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias
The 'Lambeth Conventions' is a guidance document, written in 1987 (Walker et al., 1988),
intended to be of practical value in the investigation of experimental arrhythmias induced by …
intended to be of practical value in the investigation of experimental arrhythmias induced by …
Pharmacogenomics, pharmacokinetics and pharmacodynamics: interaction with biological differences between men and women
F Franconi, I Campesi - British journal of pharmacology, 2014 - Wiley Online Library
Pharmacological response depends on multiple factors and one of them is sex–gender.
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …
Molecular pathophysiology of congenital long QT syndrome
Ion channels represent the molecular entities that give rise to the cardiac action potential,
the fundamental cellular electrical event in the heart. The concerted function of these …
the fundamental cellular electrical event in the heart. The concerted function of these …
Gender differences in clinical manifestations of Brugada syndrome
B Benito, A Sarkozy, L Mont, S Henkens… - Journal of the American …, 2008 - jacc.org
Objectives: We sought to assess differences in phenotype and prognosis between men and
women in a large population of patients with Brugada syndrome. Background: A male …
women in a large population of patients with Brugada syndrome. Background: A male …
The hERG potassium channel and hERG screening for drug-induced torsades de pointes
JC Hancox, MJ McPate, A El Harchi… - Pharmacology & …, 2008 - Elsevier
Drug-induced torsades de pointes (TdP) arrhythmia is a major safety concern in the process
of drug design and development. The incidence of TdP tends to be low, so early pre-clinical …
of drug design and development. The incidence of TdP tends to be low, so early pre-clinical …