A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

Soft matter materials, such as polymers, membranes, proteins, are often electrically charged.
This makes them water soluble, which is of great importance in technological application …

Molecular dynamics simulations are used to model proteins that diffuse to DNA, bind, and
dissociate; in the absence of any explicit interaction between proteins, or between …

Recent progress has been made in the understanding of the physical properties of
chromatin—the dense complex of DNA and histone proteins that occupies the nuclei of plant …

The ISWI proteins form the catalytic core of a subset of ATP-dependent chromatin-
remodeling activities. Here, we studied the interaction of the ISWI protein with nucleosomal …

Nucleosome positions on the DNA are determined by the intrinsic affinities of histone
proteins to a given DNA sequence and by the ATP-dependent activities of chromatin …

Understanding how chromatin is spatially and dynamically organized in the nucleus of
eukaryotic cells and how this affects genome functions is one of the main challenges of cell …

About three quarter of all eukaryotic DNA is wrapped around protein cylinders, forming
nucleosomes. Even though the histone proteins that make up the core of nucleosomes are …

The fundamental subunit of chromatin, the nucleosome, is not a static entity but can move
along DNA via either thermal or enzyme-driven movements. Here we have monitored the …

While nucleosome positioning on eukaryotic genome play important roles for genetic
regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not …