The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Macroautophagy/autophagy is a homeostatic process with multiple effects on immunity. One
of the pivotal contributions of autophagy in immunity is the cell autonomous control of …

Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …

Autophagy has broad functions in immunity, ranging from cell-autonomous defence to
coordination of complex multicellular immune responses. The successful resolution of …

Autophagy is a fundamental eukaryotic pathway that has multiple effects on immunity.
Autophagy is induced by pattern recognition receptors and, through autophagic adaptors, it …

Autophagy in Human Health and Disease | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Autophagy is a major intracellular degradative process that delivers cytoplasmic materials to
the lysosome for degradation. Since the discovery of autophagy-related (Atg) genes in the …

Phagocytic cells of the immune system must constantly survey for, recognize, and efficiently
clear the billions of cellular corpses that arise as a result of development, stress, infection, or …

Autophagy constitutes a mechanism for the sequestration and lysosomal degradation of
various cytoplasmic structures, including damaged organelles and invading …