A systematic review of polycyclic aromatic hydrocarbon derivatives: occurrences, levels, biotransformation, exposure biomarkers, and toxicity

B Peng, Q Dong, F Li, T Wang, X Qiu… - Environmental Science & …, 2023 - ACS Publications
Polycyclic aromatic hydrocarbon (PAH) derivatives constitute a significant class of emerging
contaminants that have been ubiquitously detected in diverse environmental matrixes, with …

Defining the scope of exposome studies and research needs from a multidisciplinary perspective

P Zhang, C Carlsten, R Chaleckis… - … science & technology …, 2021 - ACS Publications
The concept of the exposome was introduced over 15 years ago to reflect the important role
that the environment exerts on health and disease. While originally viewed as a call-to-arms …

[HTML][HTML] Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020–2030

MZ Jeddi, NB Hopf, H Louro, S Viegas, KS Galea… - Environment …, 2022 - Elsevier
Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised
in the European Commission's Chemicals Strategy for Sustainability (CSS). HBM can help to …

Assessing the contribution of the chemical exposome to neurodegenerative disease

S Lefevre-Arbogast, J Chaker, F Mercier… - Nature …, 2024 - nature.com
Over the past few decades, numerous environmental chemicals from solvents to pesticides
have been suggested to be involved in the development and progression of …

HExpPredict: In Vivo Exposure Prediction of Human Blood Exposome Using a Random Forest Model and Its Application in Chemical Risk Prioritization

F Zhao, L Li, P Lin, Y Chen, S Xing, H Du… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Due to many substances in the human exposome, there is a dearth of
exposure and toxicity information available to assess potential health risks. Quantification of …

Merging the exposome into an integrated framework for “omics” sciences

EJ Price, CM Vitale, GW Miller, A David, R Barouki… - IScience, 2022 - cell.com
The exposome concept encourages holistic consideration of the non-genetic factors
(environmental exposures including lifestyle) that influence an individual's health over their …

A critical review on the opportunity to use placenta and innovative biomonitoring methods to characterize the prenatal chemical exposome

T Contini, R Béranger, L Multigner… - Environmental …, 2023 - ACS Publications
Adverse effects associated with chemical exposures during pregnancy include several
developmental and reproductive disorders. However, considering the tens of thousands of …

[HTML][HTML] Innovation in regulatory approaches for endocrine disrupting chemicals: The journey to risk assessment modernization in Canada

TS Barton-Maclaren, M Wade, N Basu, S Bayen… - Environmental …, 2022 - Elsevier
Globally, regulatory authorities grapple with the challenge of assessing the hazards and
risks to human and ecosystem health that may result from exposure to chemicals that disrupt …

A comparison of four liquid chromatography–mass spectrometry platforms for the analysis of zeranols in urine

A Lazofsky, A Brinker, Z Rivera-Núñez… - Analytical and …, 2023 - Springer
Targeted biomonitoring studies quantifying the concentration of zeranols in biological
matrices have focused on liquid chromatography interfaced to mass spectrometry (LC–MS) …

CIL-ExPMRM: An Ultrasensitive Chemical Isotope Labeling Assisted Pseudo-MRM Platform to Accelerate Exposomic Suspect Screening

J Zheng, J Yang, F Zhao, B Peng… - … Science & Technology, 2023 - ACS Publications
Exposome is the future of next-generation environmental health to establish the association
between environmental exposure and diseases. However, due to low concentrations of …