Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

Gelatin-methacryloyl (GelMA) hydrogels with defined degree of functionalization as a versatile toolkit for 3D cell culture and extrusion bioprinting

I Pepelanova, K Kruppa, T Scheper, A Lavrentieva - Bioengineering, 2018 - mdpi.com
Gelatin-methacryloyl (GelMA) is a semi-synthetic hydrogel which consists of gelatin
derivatized with methacrylamide and methacrylate groups. These hydrogels provide cells …

Advances in multicellular spheroids formation

X Cui, Y Hartanto, H Zhang - Journal of the Royal …, 2017 - royalsocietypublishing.org
Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …

Could 3D models of cancer enhance drug screening?

V Brancato, JM Oliveira, VM Correlo, RL Reis… - Biomaterials, 2020 - Elsevier
Cancer is a multifaceted pathology, where cellular and acellular players interact to drive
cancer progression and, in the worst-case, metastasis. The current methods to investigate …

Engineering multi‐cellular spheroids for tissue engineering and regenerative medicine

S Kim, EM Kim, M Yamamoto, H Park… - Advanced Healthcare …, 2020 - Wiley Online Library
Multi‐cellular spheroids are formed as a 3D structure with dense cell–cell/cell–extracellular
matrix interactions, and thus, have been widely utilized as implantable therapeutics and …

3D bioprinting for drug discovery and development in pharmaceutics

W Peng, P Datta, B Ayan, V Ozbolat, D Sosnoski… - Acta biomaterialia, 2017 - Elsevier
Successful launch of a commercial drug requires significant investment of time and financial
resources wherein late-stage failures become a reason for catastrophic failures in drug …

Multiscale bioprinting of vascularized models

AK Miri, A Khalilpour, B Cecen, S Maharjan, SR Shin… - Biomaterials, 2019 - Elsevier
A basic prerequisite for the survival and function of three-dimensional (3D) engineered
tissue constructs is the establishment of blood vessels. 3D bioprinting of vascular networks …

[HTML][HTML] Nanocellulose as sustainable biomaterials for drug delivery

S Das, B Ghosh, K Sarkar - Sensors International, 2022 - Elsevier
Nanocellulose (NC) has lately appeared as a member of the major promising “green”
materials, garnering great attentiveness due to it's unique features. Several new materials …

The physical microenvironment of hematopoietic stem cells and its emerging roles in engineering applications

P Zhang, C Zhang, J Li, J Han, X Liu… - Stem Cell Research & …, 2019 - Springer
Stem cells are considered the fundamental underpinnings of tissue biology. The stem cell
microenvironment provides factors and elements that play significant roles in controlling the …