Abstract One-carbon (C1) substrates are preferred feedstocks for the biomanufacturing
industry and have recently gained attention owing to their natural abundance, low …

Based on the development of automatic devices and rapid assay methods, various high-
throughput screening (HTS) strategies have been established for improving the performance …

Engineering a biotechnological microorganism for growth on one-carbon intermediates,
produced from the abiotic activation of CO2, is a key synthetic biology step towards the …

Methanol, being electron rich and derivable from methane or CO 2, is a potentially
renewable one-carbon (C1) feedstock for microorganisms. Although the ribulose …

Highlights•One-carbon compounds can be made from CO 2 to provide renewable microbial
feedstocks.•Methanol and formate have key advantages over gaseous one-carbon …

Methanol is a liquid with high energy storage capacity that holds promise as an alternative
substrate to replace sugars in the biotechnology industry. It can be produced from CO2 or …

Metabolic engineering can have a pivotal role in increasing the environmental sustainability
of the transportation and chemical manufacturing sectors. The field has already developed …

Methanol, an organic one-carbon (C1) compound, represents an attractive alternative
carbon source for microbial fermentation. Despite considerable advancements in methanol …

Amino acid fermentation is one of the major pillars of industrial biotechnology. The multi-
billion USD amino acid market is rising steadily and is diversifying. Metabolic engineering is …

Acetyl-CoA is a fundamental metabolite for all life on Earth, and is also a key starting point
for the biosynthesis of a variety of industrial chemicals and natural products. Here we design …