Simple Summary Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with a
dismal prognosis. While immunotherapy has been deemed a breakthrough treatment for …

Irreversible electroporation (IRE), a novel non-thermal ablation technique, is utilized to
ablate unresectable solid tumors and demonstrates favorable safety and efficacy in the …

Intratumoral immunotherapy is an emerging modality for the treatment of solid tumors. Toll-
like receptor (TLR) agonists have shown promise for eliciting immune responses, but …

The response rate of pancreatic cancer to chemotherapy or immunotherapy pancreatic
cancer is low. Although minimally invasive irreversible electroporation (IRE) ablation is a …

Pancreatic cancer is a deadly disease with little response to standard therapies. Irreversible
electroporation (IRE) has emerged as a novel ablative technique for the clinical treatment of …

Memory CD8+ T cells populate non-lymphoid tissues (NLTs) following pathogen infection,
but little is known about the establishment of endogenous tumor-specific tissue-resident …

Immunotherapy has limited efficacy against locally advanced pancreatic cancer (LAPC) due
to the presence of an immunosuppressive microenvironment (ISM). Irreversible …

Simple Summary Electrochemotherapy and irreversible electroporation are primarily used
for treating patients with cutaneous and subcutaneous tumors and pancreatic cancer …

Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to
stimulate innate immune reactions against microbial infection. TLRs also play essential roles …

Cancer immunotherapy appears to be a promising treatment option; however, only a subset
of patients with cancer responds favorably to treatment. Locoregional therapy initiates a …