Experimental models to study intestinal microbes–mucus interactions in health and disease
L Etienne-Mesmin, B Chassaing… - FEMS microbiology …, 2019 - academic.oup.com
ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …
Adhesion properties of lactic acid bacteria on intestinal mucin
K Nishiyama, M Sugiyama, T Mukai - Microorganisms, 2016 - mdpi.com
Lactic acid bacteria (LAB) are Gram-positive bacteria that are natural inhabitants of the
gastrointestinal (GI) tracts of mammals, including humans. Since Mechnikov first proposed …
gastrointestinal (GI) tracts of mammals, including humans. Since Mechnikov first proposed …
Synthetic biology approaches to engineer probiotics and members of the human microbiota for biomedical applications
An increasing number of studies have strongly correlated the composition of the human
microbiota with many human health conditions and, in several cases, have shown that …
microbiota with many human health conditions and, in several cases, have shown that …
Lactobacillus Cell Surface Proteins Involved in Interaction with Mucus and Extracellular Matrix Components
L Muscariello, B De Siena, R Marasco - Current Microbiology, 2020 - Springer
The gut microbiota is a complex microbial ecosystem where bacteria, through mutual
interactions, cooperate in maintaining of wellbeing and health. Lactobacilli are among the …
interactions, cooperate in maintaining of wellbeing and health. Lactobacilli are among the …
Tripartite relationship between gut microbiota, intestinal mucus and dietary fibers: towards preventive strategies against enteric infections
T Sauvaitre, L Etienne-Mesmin… - FEMS Microbiology …, 2021 - academic.oup.com
The human gut is inhabited by a large variety of microorganims involved in many
physiological processes and collectively referred as to gut microbiota. Disrupted microbiome …
physiological processes and collectively referred as to gut microbiota. Disrupted microbiome …
Lactobacillus reuteri Inhibition of Enteropathogenic Escherichia coli Adherence to Human Intestinal Epithelium
ADS Walsham, DA MacKenzie, V Cook… - Frontiers in …, 2016 - frontiersin.org
Enteropathogenic Escherichia coli (EPEC) is a major cause of diarrheal infant death in
developing countries, and probiotic bacteria have been shown to provide health benefits in …
developing countries, and probiotic bacteria have been shown to provide health benefits in …
Lactobacillus reuteri Surface Mucus Adhesins Upregulate Inflammatory Responses Through Interactions With Innate C-Type Lectin Receptors
The vertebrate gut symbiont Lactobacillus reuteri exhibits strain-specific adhesion and
health-promoting properties. Here, we investigated the role of the mucus adhesins, CmbA …
health-promoting properties. Here, we investigated the role of the mucus adhesins, CmbA …
Structural insights into bacterial recognition of intestinal mucins
Highlights•Diversity of mucin glycans along the GI tract offers numerous recognition sites for
gut bacteria.•Commensal and pathogenic bacteria have evolved adhesins with …
gut bacteria.•Commensal and pathogenic bacteria have evolved adhesins with …
Mechanistic insights into the host-microbe interaction and pathogen exclusion mediated by the Mucus-binding protein of Lactobacillus plantarum
KS Singh, S Kumar, AK Mohanty, S Grover… - Scientific reports, 2018 - nature.com
Surface adhesins of pathogens and probiotics strains are implicated in mediating the
binding of microbes to host. Mucus-binding protein (Mub) is unique to gut inhabiting lactic …
binding of microbes to host. Mucus-binding protein (Mub) is unique to gut inhabiting lactic …
Quantifying and engineering mucus adhesion of probiotics
ZJS Mays, TC Chappell, NU Nair - ACS synthetic biology, 2020 - ACS Publications
Mucus in the gastrointestinal (GI) tract is the primary point-of-interaction between humans
and their gut microbiota. This intimates that mucus not only ensures protection against …
and their gut microbiota. This intimates that mucus not only ensures protection against …