Hydrogels and their role in biosensing applications

A Herrmann, R Haag, U Schedler - Advanced healthcare …, 2021 - Wiley Online Library
Hydrogels play an important role in the field of biomedical research and diagnostic
medicine. They are emerging as a powerful tool in the context of bioanalytical assays and …

[HTML][HTML] Functional thermoresponsive hydrogel molecule to material design for biomedical applications

S Pardeshi, F Damiri, M Zehravi, R Joshi, H Kapare… - Polymers, 2022 - mdpi.com
Temperature-induced, rapid changes in the viscosity and reproducible 3-D structure
formation makes thermos-sensitive hydrogels an ideal delivery system to act as a cell …

Universal process-inert encoding architecture for polymer microparticles

J Lee, PW Bisso, RL Srinivas, JJ Kim, AJ Swiston… - Nature materials, 2014 - nature.com
Polymer microparticles with unique, decodable identities are versatile information carriers
with a small footprint. Widespread incorporation into industrial processes, however, is limited …

[HTML][HTML] Hydrogel-based hybridization chain reaction (HCR) for detection of urinary exosomal miRNAs as a diagnostic tool of prostate cancer

J Kim, JS Shim, BH Han, HJ Kim, J Park, IJ Cho… - Biosensors and …, 2021 - Elsevier
Although urinary exosomal microRNAs (miRNAs) have recently emerged as potential
biomarkers, clinical applications are still limited due to their low concentration in small …

Hydrogel microparticles for biosensing

GC Le Goff, RL Srinivas, WA Hill, PS Doyle - European polymer journal, 2015 - Elsevier
Due to their hydrophilic, biocompatible, and highly tunable nature, hydrogel materials have
attracted strong interest in the recent years for numerous biotechnological applications. In …

Microfluidic synthesis of barcode particles for multiplex assays

Y Zhao, Y Cheng, L Shang, J Wang, Z Xie, Z Gu - Small, 2015 - Wiley Online Library
The increasing use of high‐throughput assays in biomedical applications, including drug
discovery and clinical diagnostics, demands effective strategies for multiplexing. One …

DNA hydrogel-empowered biosensing

S Khajouei, H Ravan, A Ebrahimi - Advances in colloid and interface …, 2020 - Elsevier
DNA hydrogels as special members in the DNA nanotechnology have provided crucial
prerequisites to create innovative gels owing to their sufficient stability, biocompatibility …

Microfluidic device for one-step detection of breast cancer-derived exosomal mRNA in blood using signal-amplifiable 3D nanostructure

J Lim, B Kang, HY Son, B Mun, YM Huh… - Biosensors and …, 2022 - Elsevier
Metastasis attributed to approximately 90% of cancer-related deaths; hence, the detection of
metastatic tumor–derived components in the blood assists in determining cancer recurrence …

CRISPR‐enhanced hydrogel microparticles for multiplexed detection of nucleic acids

YH Roh, CY Lee, S Lee, H Kim, A Ly… - Advanced …, 2023 - Wiley Online Library
CRISPR/Cas systems offer a powerful sensing mechanism to transduce sequence‐specific
information into amplified analytical signals. However, performing multiplexed CRISPR/Cas …

Recent advances in engineering microparticles and their nascent utilization in biomedical delivery and diagnostic applications

A Choi, KD Seo, BC Kim, DS Kim - Lab on a Chip, 2017 - pubs.rsc.org
Complex microparticles (MPs) bearing unique characteristics such as well-tailored sizes,
various morphologies, and multi-compartments have been attempted to be produced by …