The pharmacological activity, biochemical properties, and pharmacokinetics of the major natural polyphenolic flavonoid: quercetin

GES Batiha, AM Beshbishy, M Ikram, ZS Mulla… - Foods, 2020 - mdpi.com
Flavonoids are a class of natural substances present in plants, fruits, vegetables, wine,
bulbs, bark, stems, roots, and tea. Several attempts are being made to isolate such natural …

Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review

G El-Saber Batiha, A Magdy Beshbishy, L G. Wasef… - Nutrients, 2020 - mdpi.com
Medicinal plants have been used from ancient times for human healthcare as in the form of
traditional medicines, spices, and other food components. Garlic (Allium sativum L.) is an …

[HTML][HTML] Traditional uses, bioactive chemical constituents, and pharmacological and toxicological activities of Glycyrrhiza glabra L.(Fabaceae)

GES Batiha, AM Beshbishy, A El-Mleeh… - …, 2020 - ncbi.nlm.nih.gov
Traditional herbal remedies have been attracting attention as prospective alternative
resources of therapy for diverse diseases across many nations. In recent decades, medicinal …

Traditional Uses, Bioactive Chemical Constituents, and Pharmacological and Toxicological Activities of Glycyrrhiza glabra L. (Fabaceae)

G El-Saber Batiha, A Magdy Beshbishy, A El-Mleeh… - Biomolecules, 2020 - mdpi.com
Traditional herbal remedies have been attracting attention as prospective alternative
resources of therapy for diverse diseases across many nations. In recent decades, medicinal …

Molecular insights into therapeutic potentials of hybrid compounds targeting Alzheimer's disease

A Jana, A Bhattacharjee, SS Das, A Srivastava… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is one of the most complex progressive neurological disorders
involving degeneration of neuronal connections in brain cells leading to cell death. AD is …

Small-molecule drugs development for Alzheimer's disease

W Yao, H Yang, J Yang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative brain disorder
with no effective therapeutic drugs currently. The complicated pathophysiology of AD is not …

Rational drug design strategies for the development of promising multi-target directed indole hybrids as Anti-Alzheimer agents

N George, MJ Akhtar, KA Al Balushi, SA Khan - Bioorganic Chemistry, 2022 - Elsevier
Alzheimer's disease (AD) is a neurological disorder that leads to dementia ie, progressive
memory loss accompanied with worsening of thinking ability of an individual. The cause of …

Ficus exasperata Attenuates Acetaminophen‐Induced Hepatic Damage via NF‐κB Signaling Mechanism in Experimental Rat Model

BO Adetuyi, OA Adebisi, OA Adetuyi… - BioMed research …, 2022 - Wiley Online Library
Ficus exasperata has been used to treat ulcer, diabetes, fever, and a variety of stress‐
related disorders. Acetaminophen (APAP) overdose is the most common cause of drug …

Natural products from plants and algae for treatment of Alzheimer's disease: A review

J Klose, C Griehl, S Roßner, S Schilling - Biomolecules, 2022 - mdpi.com
Neurodegenerative disorders including Parkinson's disease (PD), Huntington's disease
(HD) and the most frequent, Alzheimer's disease (AD), represent one of the most urgent …

Virtual screening and hit selection of natural compounds as acetylcholinesterase inhibitors

M Atanasova, I Dimitrov, S Ivanov, B Georgiev… - Molecules, 2022 - mdpi.com
Acetylcholinesterase (AChE) is one of the classical targets in the treatment of Alzheimer's
disease (AD). Inhibition of AChE slows down the hydrolysis of acetycholine and increases …