Survivin: A molecular biomarker in cancer
PK Jaiswal, A Goel, RD Mittal - Indian Journal of Medical …, 2015 - journals.lww.com
Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …
and blocks cell death, is highly expressed in most cancers and is associated with a poor …
Inhibitors of apoptosis: clinical implications in cancer
Inhibitor of apoptosis (IAP) family comprises a group of endogenous proteins that function as
main regulators of caspase activity and cell death. They are considered the main culprits in …
main regulators of caspase activity and cell death. They are considered the main culprits in …
Survivin, a molecular target for therapeutic interventions in squamous cell carcinoma
Squamous cell carcinoma (SCC) is the most common cancer worldwide. The treatment of
locally advanced disease generally requires various combinations of radiotherapy, surgery …
locally advanced disease generally requires various combinations of radiotherapy, surgery …
The survivin molecule as a double‐edged sword in cellular physiologic and pathologic conditions and its role as a potential biomarker and therapeutic target in cancer
A Rafatmanesh, M Behjati, N Mobasseri… - Journal of Cellular …, 2020 - Wiley Online Library
Survivin is a member of the family of apoptosis inhibitory proteins with increased expression
level in most cancerous tissues. Evidence shows that survivin plays regulatory roles in …
level in most cancerous tissues. Evidence shows that survivin plays regulatory roles in …
BIRC5 Gene Polymorphisms Are Associated with a Higher Stage of Local and Regional Disease in Oral and Oropharyngeal Squamous Cell Carcinomas
Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
(OPSCC) are the most common types of cancers in the head and neck region (HNSCC) …
An insight into Survivin in relevance to hematological, biochemical and genetic characteristics in tobacco chewers with oral squamous cell carcinoma
ST Yesupatham, CD Dayanand… - Cells, 2023 - mdpi.com
Background: Survivin is an inhibitor of apoptosis protein (IAP), encoded by the Baculoviral
IAP Repeat Containing 5 (BIRC5) gene located on q arm (25.3) on chromosome 17. It is …
IAP Repeat Containing 5 (BIRC5) gene located on q arm (25.3) on chromosome 17. It is …
Overview of role of survivin in cancer: expression, regulation, functions, and its potential as a therapeutic target
X Fang, X Cao, J Xiao, Y Hu, M Chen… - Journal of Drug …, 2024 - Taylor & Francis
Survivin holds significant importance as a member of the inhibitor of apoptosis protein (IAP)
family due to its predominant expression in tumours rather than normal terminally …
family due to its predominant expression in tumours rather than normal terminally …
Survivin gene polymorphism association with papillary thyroid carcinoma
N Yazdani, FA Sayahpour, V Haghpanah… - … -Research and Practice, 2012 - Elsevier
Survivin expression is correlated with suppression of apoptosis in human solid tumors. A
polymorphism at position− 31 (G/C)(rs 9904341) has been associated with cancer risk in …
polymorphism at position− 31 (G/C)(rs 9904341) has been associated with cancer risk in …
Survivin SNP-carcinogen Interactions in Oral Cancer
CJ Weng, YH Hsieh, MK Chen… - Journal of dental …, 2012 - journals.sagepub.com
In Taiwan, oral cancer is causally associated with environmental carcinogens. Survivin is an
anti-apoptotic protein and is generally considered a marker of malignancy. The current study …
anti-apoptotic protein and is generally considered a marker of malignancy. The current study …
Functional polymorphisms in promoter survivin gene and its association with susceptibility to bladder cancer in North Indian cohort
PK Jaiswal, A Goel, A Mandhani, RD Mittal - Molecular biology reports, 2012 - Springer
Survivin is a member of novel inhibitor of apoptosis protein family which expressed in
human cancers. The molecular detection of bladder cancer by targeting Survivin as a novel …
human cancers. The molecular detection of bladder cancer by targeting Survivin as a novel …