Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics

E Paleček, J Tkáč, M Bartosik, T Bertók… - Chemical …, 2015 - ACS Publications
The present advances in biology are related to progress in genomics, proteomics, and other
“-omics”, including glycomics, working with a large amount of data regarding human and …

Self-contained microfluidic systems: a review

M Boyd-Moss, S Baratchi, M Di Venere… - Lab on a Chip, 2016 - pubs.rsc.org
Microfluidic systems enable rapid diagnosis, screening and monitoring of diseases and
health conditions using small amounts of biological samples and reagents. Despite these …

Calibration-free electrochemical biosensors supporting accurate molecular measurements directly in undiluted whole blood

H Li, P Dauphin-Ducharme, G Ortega… - Journal of the …, 2017 - ACS Publications
The need to calibrate to correct for sensor-to-sensor fabrication variation and sensor drift has
proven a significant hurdle in the widespread use of biosensors. To maintain clinically …

Paper electrochemical device for detection of DNA and thrombin by target-induced conformational switching

JC Cunningham, NJ Brenes, RM Crooks - Analytical chemistry, 2014 - ACS Publications
Here, we report a strategy for the design of an inexpensive paper analytical device (PAD) for
quantitative detection of oligonucleotides and proteins. Detection is based on the principle of …

Dynamic Bio‐Barcode Assay Enables Electrochemical Detection of a Cancer Biomarker in Undiluted Human Plasma: A Sample‐In‐Answer‐Out Approach

SM Traynor, GA Wang, R Pandey, F Li… - Angewandte …, 2020 - Wiley Online Library
There is a need for biosensing systems that can be operated at the point‐of‐care (POC) for
disease screening and diagnostics and health monitoring. In spite of this, simple to operate …

A nucleic acid nanostructure built through on-electrode ligation for electrochemical detection of a broad range of analytes

S Somasundaram, CJ Easley - Journal of the American Chemical …, 2019 - ACS Publications
For an assay to be most effective in point-of-care clinical analysis, it needs to be economical,
simple, generalizable, and free from tedious workflows. While electrochemistry-based DNA …

Expanding the scope of protein-detecting electrochemical DNA “scaffold” sensors

D Kang, C Parolo, S Sun, NE Ogden, FW Dahlquist… - ACS …, 2018 - ACS Publications
The ability to measure the levels of diagnostically relevant proteins, such as antibodies,
directly at the point of care could significantly impact healthcare. Thus motivated, we explore …

[HTML][HTML] Importance of IP-10 as a biomarker of host immune response: Critical perspective as a target for biosensing

S Madhurantakam, ZJ Lee, A Naqvi… - Current Research in …, 2023 - Elsevier
While the exploration into biomolecules for diagnostic and prognostic devices continues to
develop, many molecules continue to be examined for individual diseases or treatments …

New architecture for reagentless, protein-based electrochemical biosensors

D Kang, S Sun, M Kurnik, D Morales… - Journal of the …, 2017 - ACS Publications
Here we demonstrate a new class of reagentless, single-step sensors for the detection of
proteins and peptides that is the electrochemical analog of fluorescence polarization …

Specific Picomolar Detection of a Breast Cancer Biomarker HER‐2/neu Protein in Serum: Electrocatalytically Amplified Electroanalysis by the Aptamer/PEG‐Modified …

R Salimian, L Kékedy‐Nagy… - …, 2017 - Wiley Online Library
Specific and sensitive electroanalysis of blood‐circulating protein cancer biomarkers is often
complicated by interference from serum proteins nonspecifically adsorbing at the biosensing …